Renal Angiomyolipoma: 6 Case Reports and Literature Review

Abstract

We report 6 cases of renal angiomyolipomas and review the pertinent literature concerning this disease. One case involved the rare association of tuberous sclerosis and pregnancy. Another patient without tuberous sclerosis had renal cell carcinoma and later suffered a contralateral angiomyolipoma. The pathological conditions of renal angiomyolipomas with and without tuberous sclerosis are discussed. Since angiomyolipomas present with multiple clinical similarities to renal cell carcinoma, the primary task for the clinician is to differentiate this hamartoma from carcinoma. The distinguishing characteristics and the clinical management of renal angiomyolipomas are discussed.

Renal Tumors in Adult Saudi Patients: A Review of 43 Cases

“…Renal angiomyolipoma accounted for 14% of the cases in our group, which is much higher than that reported in the literature of 1% of all surgically excised tumors. 8 Renal angiomyolipoma is known to affect females predominantly; 9 this is consistent with our findings where all patients but one were females. Fifty percent of all renal angiomyolipoma occur in tuberous sclerosis patients and up to 80% of patients with tuberous sclerosis exhibit angiomyolipoma.…”

“…Fifty percent of all renal angiomyolipoma occur in tuberous sclerosis patients and up to 80% of patients with tuberous sclerosis exhibit angiomyolipoma. 9,10 Only one of our patients had the stigmas of tuberous sclerosis complex. Renal angiomyolipoma in association with renal cell carcinoma has been described previously.…”

Tuberous sclerosis complex-associated renal angiomyolipomas: A single center study of 17 consecutive cases

“…Renal cysts occur in 20% of patients with TSC and tend to stabilize with increasing age (16). AML is the most common renal manifestation and 66.6% of TSC patients develop multiple renal AML (17)(18)(19). Treatment for diseases of the nervous system has markedly improved; however, long-term survival depends on the effective control of kidney disease in TSC patients.…”

Bilateral Renal Angiomyolipoma: Involvement of the Contralateral Kidney after 25 Years – An Unusual Case

“…Histologically angiomyolipoma contains dysplastic vessels, spindle-like smooth muscle fibers and fat [ 19]. In the differential diagnosis it is difficult to distinguish angiomyolipoma from lipomyosarcomas, and in many cases this is only possible under the electron microscope or with immunohistochemical techniques [12], An exact diagnosis of such tumors is important for the correct management of these patients and for avoiding unneces sary operations or false therapeutic measures.…”