Renal angiomyolipoma

Abstract

SUMMARY INTRODUCTION Angiomyolipoma is one of the most common benign solid renal tumors. We investigated the characteristics of renal angiomyolipomas and the clinical outcomes of patients in the last thirteen years. METHODS The medical records of the patients who underwent nephrectomy were reviewed retrospectively from July 2005 to May 2018. The laboratory data, radiology, and pathology reports were recorded. Patients diagnosed with angiomyolipoma were included in the study. RESULTS A total of 28 patients were included in the study, eight of them male. The mean age of the patients was 55.89+14.49 years. The patients were treated with open and laparoscopic techniques. Partial nephrectomy was performed in 12 patients(42.85%). After pathological examination, 23 patients were diagnosed as fat rich, four patients as fat poor, and one as epithelioid angiomyolipoma. There were no recurrences in the follow-up 91.21+48.31 months. CONCLUSION Angiomyolipoma is a rare renal tumor in daily urology practice. Clinicians must be aware of its complications and manage patients well.

Giant renal pseudoaneurysm complicating angiomyolipoma in a patient with tuberous sclerosis complex: An unusual case report and review of the literature

“…Renal angiomyolipoma was first defined by Fischer in 1911, which predominantly affects females rather than males [ 8 ]. Some studies have suggested that AMLs can present in a wide age range from 19 to 93 years with overall prevalence being as high as 0, 3% [ 1 , 5 ].…”

“…Magnetic resonance imaging (MRI) has a high sensitivity for detecting fat tissues, so it is useful to differentiate AML from other renal masses . However, MRI has a high cost and is time-consuming when compared to ultrasonography and CT [ 8 ]. Angiography of the renal artery is a useful invasive method to provide obscure anatomical data and to treat the corresponding causes of bleeding [ 14 ].…”

“…Microwave tumor ablation, radiofrequency, and cryoablation, are other possible treatments for small tumors. The only mTOR inhibitor approved for the treatment of renal angiomyolipoma is everolimus, which is indicated in the treatment of adult patients with TSC-associated angiomyolipoma who are at risk of complications but do not need immediate surgery [ 1 , 8 , 10 ]. In our case, the renal bleeding was successfully treated with superselective renal embolization with a favorable outcome.…”

Renal angiomyolipoma with inferior vena cava and right atrium extension in patient with tuberous sclerosis complex: a rare case report and literature review.

“…Angiomyolipoma is one of the most common benign renal tumors and accounts for 0.3-3% of all renal masses. [1] It contains fat, blood vessels, and smooth muscles in different proportions. [2] It mainly includes two histology types: classical and epithelioid [3] .…”

Epithelioid angiomyolipoma with tumor thrombus in IVC and right atrium

“…These can show predominance of smooth muscle elements or adipose tissue, depending on which it can be labelled as leiomyoma-like or lipoma-like. 2 In a recent study by Çalışkan et al 9 the authors described 28 cases of renal AMLs and classified in three categories: fat-rich (82.1%), fatpoor (14.3%) and epithelioid (3.6%). In the study by Aydin et al 3 classic AMLs accounted for 76.8% cases while epithelioid variants, epithelial cysts and microscopic AMLs were noted in 7.7% cases, 6.7% cases and 10.8% cases, respectively.…”