Renal fluoride excretion as a useful parameter for monitoring hydrofluoric acid-exposed persons

Reference Values of Renal Excretion of Fluoride

“…Our results correspond to other studies (3). Zober et al (6) found 0.5 mg/24 h (n = 9). The results of balance studies (drinking water, food intake/urine) cannot directly be compared with the present study, because 24 ^samples were always used (2,4,11).…”

“…In the available studies on the fluoride excretion of exposed workers the data were sometimes compared with small reference groups of non-exposed persons (5,6). the results, however, do not allow a general conclusion; the same is true of laboratory studies (7).…”

Hydrogen fluoride and inorganic fluorine compounds (Fluorides) [BAT Value Documentation, 1994]

“…Part of the internal fluoride exposure is deposited long-term in the skeleton (12,15,16). With increasing fluoride exposure the bone deposit seems to increase marginally (14).…”

“…20 % via perspiration. The excretion rate is said to decrease with increasing internal fluoride exposure (13,14). Part of the internal fluoride exposure is deposited long-term in the skeleton (12,15,16).…”

“…The determination of the fluoride content in human bones (32) is not a method for routine health surveillance because the necessary samples must be obtained by biopsy (17). Rather, the possible internal fluoride body burden must be determined by other biological indicators, whereby the fluoride analysis in the blood and/or urine samples has proved appropriate for the correlating evaluation of internal fluoride exposure (10,14,33). A direct linear relationship between the external fluoride exposure and the renal fluoride excretion was ascertained.…”