2016
DOI: 10.1111/bju.13620
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Renal fossa recurrence after nephrectomy for renal cell carcinoma: prognostic features and oncological outcomes

Abstract: ObjectivesTo describe the clinicopathological features associated with increased risk of renal fossa recurrence (RFR) after radical nephrectomy (RN) and to describe the prognostic features associated with cancer-specific survival (CSS) among patients with RFR treated with primary locally directed therapy, systemically directed therapy or expectant management. Patients and MethodsThe records of 2 502 patients treated with RN for unilateral, sporadic, localized renal cell carcinoma (RCC) between 1970 and 2006 we… Show more

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Cited by 34 publications
(39 citation statements)
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“…32 Technical feasibility also is contingent upon a patient's burden of comorbidity and functional status, which may determine the safety of submitting the patient to general anesthesia and a potentially complex operation. In addition to the urologist, depending on the location, a surgical team comprised of members with expertise in cardiothoracic, hepatobiliary, colorectal, and endocrine surgery; surgical oncology; orthopedics; and neurosurgery may need to be involved in addition to an experienced anesthesia team.…”
Section: Surgical Considerations and Complications Related To Metastamentioning
confidence: 99%
See 1 more Smart Citation
“…32 Technical feasibility also is contingent upon a patient's burden of comorbidity and functional status, which may determine the safety of submitting the patient to general anesthesia and a potentially complex operation. In addition to the urologist, depending on the location, a surgical team comprised of members with expertise in cardiothoracic, hepatobiliary, colorectal, and endocrine surgery; surgical oncology; orthopedics; and neurosurgery may need to be involved in addition to an experienced anesthesia team.…”
Section: Surgical Considerations and Complications Related To Metastamentioning
confidence: 99%
“…54 Indeed, radiotherapy has demonstrated utility in the management of mRCC both as monotherapy and as adjuvant therapy to surgical resection [55][56][57] and in the management of osseous, 58-61 pulmonary, 62 brain, 63 and pancreatic metastases. 54 Indeed, radiotherapy has demonstrated utility in the management of mRCC both as monotherapy and as adjuvant therapy to surgical resection [55][56][57] and in the management of osseous, 58-61 pulmonary, 62 brain, 63 and pancreatic metastases.…”
Section: Radiation Therapymentioning
confidence: 99%
“…Patients undergoing surgery for symptomatic recurrences have a higher rate of incomplete resection of recurrence, positive surgical margins and worse survival compared to surgery without symptoms. [41][42][43] Extensive tumour recurrence reduces the possibility of complete surgical resection, which is standard therapy for patients with local recurrence or resectable solitary metastasis. Furthermore, an early diagnosis of metastatic disease relapse may enhance efficacy of systemic therapy or allow for metastasectomy if the tumour burden is low.…”
Section: Kassouf Et Al Non-metastatic Rcc Followupmentioning
confidence: 99%
“…44,45 Tumour grade, local extent of the primary tumour, presence of nodal metastasis, and histological subtype are predictors of the disease relapse (Level of Evidence 3). 41,[46][47][48] As such, these variables should be noted because they contribute to important prognostic information.…”
Section: Prognostic Variablesmentioning
confidence: 99%
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