Renal parenchymal malacoplakia: a different stage of xanthogranulomatous pyelonephritis?

Yiğiter, Murat; Ilgici, Dilek; Çelik, Mustafa; Arda, İrfan Serdar; Hiçsönmez, Akgün

doi:10.1016/j.jpedsurg.2007.05.005

Cited by 12 publications

(11 citation statements)

References 18 publications

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“…This condition is characterized by foamy histiocyte accumulation in the renal parenchyma and may represent a variant of XGP. 9 Typical sonographic features of malakoplakia include hyperechoic renal parenchyma from plaque confluence. 10 Alternatively, hypoechoic lesions associated with parenchymal distortion may also be seen.…”

Section: Discussionmentioning

confidence: 99%

Replacement Lipomatosis of the Kidney

Ginat

Bhatt

Dogra

2008

Journal of Ultrasound in Medicine

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eplacement renal sinus lipomatosis (RRSL) is an uncommon disorder characterized by renal sinus fat proliferation resulting from renal parenchymal atrophy, inflammation, or calculous disease. We present the sonographic features of RRSL secondary to nephrolithiasis in a 75-year-old man. The patient was successfully treated with lithotripsy. Several entities can resemble the appearance of RRSL, including malakoplakia, fat-containing tumors, and xanthogranulomatous pyelonephritis (XGP). Sonography and a high index of suspicion are helpful in making a diagnosis of RRSL.Received April 20, 2008, Case ReportThe patient was a 75-year-old man with a history of radical cystectomy for bladder carcinoma with a urostomy. He had intermittent urolithiasis, in which calculi were passed through his urostomy. The patient underwent sonography to assess for renal stones. Sonography revealed an enlarged left kidney marked by a proliferation of renal sinus fat visualized as homogeneously increased echogenicity and virtually replacing the entire renal parenchyma. Overall, the left kidney measured 13.1 cm. However, a small atrophic renal cortex was identified in the periphery. Moderate focal hydronephrosis was apparent distally, indicating a mass effect of sinus fat on the calyceal system. A large calculus was situated in the pelviureteral junction (Figure 1). Renal arterial flow was preserved. Sonographic findings of the right kidney were unremarkable except for a diffusely echogenic sinus, indicative of a fatty component compatible with age-related renal sinus lipomatosis (Figure 2).

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Section: Discussionmentioning

confidence: 99%

Replacement Lipomatosis of the Kidney

Ginat

Bhatt

Dogra

2008

Journal of Ultrasound in Medicine

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“…Although it is easy to diagnose a fatty mass on CT, to characterize this entity preoperatively as renal replacement lipomatosis is a clinical challenge. In almost all reported cases, the diagnosis was confirmed on histopathology only (1)(2)(3)(4)(5)(6). Hence, the best treatment in such cases is excision of fatty mass intotal.…”

Section: Discussionmentioning

confidence: 97%

Idiopathic renal replacement lipomatosis: A diagnostic and therapeutic challenge

et al. 2018

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“…Two benign closely related entities are malakoplakia and megalocytic interstitial nephritis. The hallmark of both lesions is the periodic acid-shift diastase-positive material in the cytoplasm of the macrophages while in malakoplakia Michaelis-Gutmann bodies are characteristic of the lesion 1 21…”

Section: Discussionmentioning

confidence: 99%

Xanthogranulomatous pyelonephritis presenting as a pseudotumour in a 5-year-old boy

et al. 2012

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SummaryXanthogranulomatous pyelonephritis (XGPN) is a rare, severe and atypical form of chronic pyelonephritis. It is characterised by destruction of the renal parenchyma and replacement with a chronic inflammatory infiltrate and lipid-laden macrophages resulting in a non-functional kidney. The authors report a case of a 5-year-old boy presented with a history of abdominal pain, malaise, anorexia and weight loss for 2 months. Physical examination revealed a large flank mass and the child was directed to the oncology unit on suspicion of renal tumour. Based on clinical examination and imaging, the presumptive diagnosis of XGPN of the left kidney was made. A left transperitoneal nephrectomy was performed and the histology confirmed the diagnosis. Although rare, XGPN is a clinically important entity that should be considered in the differential diagnosis of an atypical-appearance renal mass in paediatric age. BACKGROUND

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Renal parenchymal malacoplakia: a different stage of xanthogranulomatous pyelonephritis?

Cited by 12 publications

References 18 publications

Replacement Lipomatosis of the Kidney

Replacement Lipomatosis of the Kidney

Idiopathic renal replacement lipomatosis: A diagnostic and therapeutic challenge

Xanthogranulomatous pyelonephritis presenting as a pseudotumour in a 5-year-old boy

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