Reoperations After the Ross Procedure

Next-generation tissue-engineered heart valves with repair, remodelling and regeneration capacity

“…The current trend to preferentially use bioprostheses also in the younger population 37 , comes at the cost of a structural valve failure, due to progressive calcification of the leaflets within 10-15 years after implantation 43 . On the other hand, valve durability up to 20 years has been reported for elderly patients 44 . Anti-mineralization treatments were developed to further improve bioprosthetic valve durability and to limit the onset of calcification 45 .…”