Reparative Bone Regeneration at Use of Local Antibacterial Carriers in Purulent Osteomyelitis (Experimental Study)

Aim. to present the results of treatment of long bones chronic osteomyelitis using local cement reinforcing antibacterial implant. Material and methods. the implant is made intraoperatively using polymethylmethacrylate. it was used in main group (n=30), while conventional treatment was applied in comparison group (n=30). Results. Better early and remote outcomes were shown in main group including more effective and earlier suppression of infectious process, more than 2-fold decrease of recurrent infection incidence, minimization of risk of pathological fracture due to internal reinforcement, early recovery of extremity's function, creation of favorable conditions for bone structures restoration, substitution of post-resection bone defect and following organotypic reorganization of bone tissue.

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Efficiency of local cement reinforcing antibacterial implants in surgical treatment of long bones chronic osteomyelitis

Dzyuba

Ерофеев

et al. 2016

Khir. Z. im. N.I. Pirogova

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Elaboration of Universal Approaches to the Treatment of Long Bone Osteomyelitis on the Basis of Reinforced Local Antibacterial Carriers

Dzyuba

Резник

Ерофеев

et al. 2016

Vestn. travmatol. ortop. im. N.N. Priorova

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Treatment results are presented for 86 patients with long bone osteomyelitis of different genesis (hematogenous, posttraumatic, postoperative). To determine the location of the implant the Cierny-Mader classification was used. In the main group (n=46) debridement of the osteomyelitic focus and placement of local reinforcing antibacterial polymethyl methacrylate implant with pathogen-specific antibiotics were performed. In the control group (n=40) traditional treatment techniques were used. Application of the proposed technique enabled to achieve 1.9 times decrease of infection relapse, to minimize the risk of pathological bone fractures due to its internal reinforcement and to achieve early functional restoration of the extremity.

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Reparative Bone Regeneration at Use of Local Antibacterial Carriers in Purulent Osteomyelitis (Experimental Study)

Cited by 2 publications

References 4 publications

Efficiency of local cement reinforcing antibacterial implants in surgical treatment of long bones chronic osteomyelitis

Efficiency of local cement reinforcing antibacterial implants in surgical treatment of long bones chronic osteomyelitis

Elaboration of Universal Approaches to the Treatment of Long Bone Osteomyelitis on the Basis of Reinforced Local Antibacterial Carriers

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