corneal tomography is an important tool to identify and follow up eyes with keratoconus. our study evaluate the repeatability of the automatic measurements provided in keratoconic eyes by a new anterior-segment optical coherence tomographer (AS-oct) combined with placido-disk topography (MS-39, CSO) and assess their agreement with the corresponding measurements taken with a rotating Scheimpflug camera combined with Placido-disk topography (Sirius, CSO). Mean simulated keratometry, posterior and total corneal power, total corneal astigmatism, corneal asphericity, thinnest corneal thickness, epithelial thickness, corneal diameter, and aqueous depth were evaluated. Repeatability was assessed using test-retest variability, the coefficient of variation, and the intraclass correlation coefficient; agreement was assessed by the 95% limits of agreement. Good repeatability was achieved for most parameters. Moderate repeatability was found for total corneal astigmatism measurements. the repeatability of mean simulated keratometry and total corneal power measurements worsened with more severe stages of keratoconus with a statistically significant relationship between the individual coefficient of variation and corneal power values. Agreement with the Scheimpflug camera was moderate for aqueous depth and thinnest corneal thickness and poor for most other measured parameters. the good repeatability of automatic measurements suggests the new AS-oct device to be a viable option in clinical practice of eyes with keratoconus. Keratoconus is a non-inflammatory ectasic disease characterized by progressive thinning and steepening and an apical cone-shaped protrusion of the cornea 1,2. The introduction of corneal topography first and corneal tomography later enabled researchers to develop several methods to identify keratoconic eyes 3-7. Accurate corneal imaging is now highly desirable to diagnose keratoconus, especially in its earlier stages, when visual acuity is still good. Modern anterior segment imaging techniques, such as Scheimpflug photography and optical coherence tomography (OCT), have significantly improved our ability to identify eyes with keratoconus, as they also provide pachymetric data and posterior corneal curvature measurements. Although anterior corneal surface parameters may be sufficient to discriminate between normal eyes and eyes with clinical keratoconus, using the data from both corneal surfaces as well as corneal thickness increases precision, sensitivity, specificity, and accuracy, thus significantly improving the ability to differentiate between normal eyes and subclinical keratoconus suspect eyes 7. One of the main limitations of Scheimpflug imaging is the low resolution and relatively poor quality of anterior segment scans. In this regard, anterior segment OCT (AS-OCT) is known to produce better images with higher definition. The higher resolution has made it possible, for example, to measure the corneal epithelial thickness 8-10. A parameter that has never been evaluated by Scheimpflug cameras. The purp...