Repetitive transcranial magnetic stimulation (rTMS) combined with multi-modality aphasia therapy for chronic post-stroke non-fluent aphasia: A pilot randomized sham-controlled trial

Repetitive transcranial magnetic stimulation for post-stroke non-fluent aphasia: a systematic review and meta-analysis of randomized controlled trials

“…Out of the 48 studies ( 4 , 23 , 35 – 80 ), 37 studies ( 35 – 37 , 39 – 49 , 51 , 52 , 54 – 66 , 68 , 69 , 72 – 74 , 76 , 78 , 79 ) had reported diagnostic criteria for stroke and 35 ( 4 , 35 – 39 , 41 – 53 , 55 , 57 – 60 , 62 – 65 , 67 – 70 , 74 , 76 , 77 ) for aphasia. In 43 studies ( 4 , 23 , 35 – 52 , 54 – 65 , 67 – 76 , 78 , 80 ), the age of the patient was reported as mean ± standard deviation, while two studies ( 53 , 66 ) reported specific age information for each patient, and the age range was reported in two studies ( 77 , 79 ).…”

“…Out of the 48 studies ( 4 , 23 , 35 – 80 ), 37 studies ( 35 – 37 , 39 – 49 , 51 , 52 , 54 – 66 , 68 , 69 , 72 – 74 , 76 , 78 , 79 ) had reported diagnostic criteria for stroke and 35 ( 4 , 35 – 39 , 41 – 53 , 55 , 57 – 60 , 62 – 65 , 67 – 70 , 74 , 76 , 77 ) for aphasia. In 43 studies ( 4 , 23 , 35 – 52 , 54 – 65 , 67 – 76 , 78 , 80 ), the age of the patient was reported as mean ± standard deviation, while two studies ( 53 , 66 ) reported specific age information for each patient, and the age range was reported in two studies ( 77 , 79 ). Except for two studies ( 50 , 59 ) that failed to disclose the post-stroke time, the mean course of disease for patients in the other 44 studies ( 4 , 23 , 35 – 49 , 51 , 52 , 54 – 58 , 60 – 65 , 67 – 80 ) ranged from 6.9 days to 4.46 years, and two studies ( ...…”

“…In 43 studies ( 4 , 23 , 35 – 52 , 54 – 65 , 67 – 76 , 78 , 80 ), the age of the patient was reported as mean ± standard deviation, while two studies ( 53 , 66 ) reported specific age information for each patient, and the age range was reported in two studies ( 77 , 79 ). Except for two studies ( 50 , 59 ) that failed to disclose the post-stroke time, the mean course of disease for patients in the other 44 studies ( 4 , 23 , 35 – 49 , 51 , 52 , 54 – 58 , 60 – 65 , 67 – 80 ) ranged from 6.9 days to 4.46 years, and two studies ( 53 , 66 ) reported specific course of disease for each patient. Of the total studies, 39 studies ( 4 , 35 – 43 , 45 – 48 , 51 – 55 , 58 – 70 , 72 – 74 , 77 – 80 ) specifically reported that the patients were right-handed, whereas the remaining 9 studies ( 23 , 44 , 49 , 50 , 56 , 57 , 71 , 75 , 76 ) failed to furnish this information.…”

“…Except for two studies ( 50 , 59 ) that failed to disclose the post-stroke time, the mean course of disease for patients in the other 44 studies ( 4 , 23 , 35 – 49 , 51 , 52 , 54 – 58 , 60 – 65 , 67 – 80 ) ranged from 6.9 days to 4.46 years, and two studies ( 53 , 66 ) reported specific course of disease for each patient. Of the total studies, 39 studies ( 4 , 35 – 43 , 45 – 48 , 51 – 55 , 58 – 70 , 72 – 74 , 77 – 80 ) specifically reported that the patients were right-handed, whereas the remaining 9 studies ( 23 , 44 , 49 , 50 , 56 , 57 , 71 , 75 , 76 ) failed to furnish this information. Duration of the intervention in 45 studies ( 4 , 23 , 35 , 36 , 38 – 40 , 42 – 46 , 48 – 80 ) spanned from 2 to 4 weeks, except for 2 studies ( 37 , 41 ) with an intervention duration of 30 days and one ( 47 ) with 8 weeks.…”

“…Stroke remains a primary cause of mortality and morbidity globally ( 1 , 2 ). Approximately 38% of adult stroke victims are subsequently diagnosed with aphasia ( 3 , 4 ), which further worsens the prognosis for these patients. The severity of aphasia is useful in predicting the functional autonomy of patients, as well as their short-term and long-term recovery outcomes following a stroke ( 5 , 6 ).…”