Replacing dairy fat with rapeseed oil causes rapid improvement of hyperlipidaemia: a randomized controlled study

Abstract

Abstract. Iggman D, Gustafsson I-B, Berglund L, Vessby B, Marckmann P, Risérus U (Clinical Nutrition and Metabolism,

Potential role of milk fat globule membrane in modulating plasma lipoproteins, gene expression, and cholesterol metabolism in humans: a randomized study

“…Milk fat (e.g., butter) has long been recognized as having cholesterol-raising effects that are caused by the high content of long-chain SFAs, especially when compared with that of vegetable oils rich in unsaturated fatty acids (1,2). In Finland, population-based interventions aimed at reducing butter specifically resulted in major decreases in serum cholesterol concentrations and the incidence of CVD (3).…”

Interactive effects of dietary protein level and oil source on proximate composition and fatty acid composition in common carp (Cyprinus carpio L.)

“…It contains moderate levels of LA and a-linolenic acid (ALA) at a ratio of 2:1 (Iggman et al, 2011) and it is expected that here will be a modest deposition of these fatty acids in fish flesh and an increase of the endogenous conversion of ALA to EPA and DHA, as previously was shown for grass carp (Du et al, 2005(Du et al, , 2006(Du et al, , 2008. RO contains high levels of MUFA, especially oleic acid (OA), which are preferred fatty acids for energy production in common carp (Mraz et al, 2012), so growth performance of the carp should not be compromised.…”

What is a healthy Nordic diet? Foods and nutrients in the NORDIET study

“…The replacement of foods rich in SFA and trans fatty acids with foods rich in PUFA has favourable effects on cardiovascular risk factors (22, 34–36). Although beneficial effects on diabetes risk and insulin sensitivity have been observed, the results are less consistent (37).…”

“…In hyperlipidemic subjects, rapeseed oil has more favourable effects on total cholesterol/high-density lipoprotein ratio and triglycerides than a diet rich in high-fat dairy products (22), especially when the diet consists of >35 E% fat (22). In this study, total fat intake was much lower (27 E%) and most likely explained the reduction in HDL-C (1).…”

“…Approximately 80% of food items included in ND should be possible to grow in the Nordic countries. Food groups in the study were based on commonly available specific key nutrients inspired by earlier reports (Table 1) (19–21), for instance, rapeseed oil rich in oleic, linoleic and α-linolenic acids (22, 23). Fish in general, especially fatty fish, was a natural ingredient in ND, and low-fat dairy products (milk, yoghurt and cheese for cooking) (6, 10, 24), whole grain cereals in general (25–27) and specific whole grain cereals based on oat and barley (28, 29) and rye (17, 30) were recommended.…”