Réplication du virus de l’hépatite E dans les cellules intestinales

Advances in Hepatitis E Virus

“…Very importantly, the discovery of HEV as the causative agent of an intriguing chronic liver disease in transplant patients in 2010 highlighted its ability to cause chronic infection in immunosuppression settings [1][2][3]. More recently, the notion that hepatitis E might be considered a systemic disease rather than solely a liver disease was supported by the adverse effects on diverse tissues attributed to the infection, and importantly, by the ability of HEV to infect multiple cell types, including peripheral blood mononuclear cells, enterocytes, endometrial cells, and placental cells [4][5][6][7].…”