Reply to “Comment on: Effects of Nigella Sativa on Type-2 Diabetes Mellitus: A Systematic Review”

Hamdan, Amiza; Idrus, Ruszymah Haji; Mokhtar, Mohd Helmy

doi:10.3390/ijerph17093111

Cited by 1 publication

(1 citation statement)

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“…It has been shown that different organic extracts of black cumin such as hydroacetone extract have the ability to inhibit α-amylase [ 97 ] ( Figure 6 ). Also, the consumption of 5 g/day of black cumin for six months caused a decrease in glycated hemoglobin [ 98 ]. On the other hand, the nanoparticles formed from silver nitrates showed inhibitory activity on both α-amylase enzymes and α-glucosidase which was higher than that obtained by aqueous extract or even by acarbose used as a control [ 99 ].…”

Section: Pharmacological Properties Of Nigella Sativamentioning

confidence: 99%

Nigella sativa L. Phytochemistry and Pharmacological Activities: A Review (2019–2021)

et al. 2021

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Medicinal and aromatic plants are mainly characterized by the presence of different bioactive compounds which exhibit various therapeutic activities. In order to investigate the different pharmacological properties of different Nigella sativa extracts, a multitude of research articles published in the period between 2019 and 2021 were obtained from different databases (Scopus, Science Direct, PubMed, and Web of Science), and then explored and analyzed. The analysis of the collected articles allows us to classify the phytochemicals and the pharmacological activities through their underlying molecular mechanisms, as well as to explore the pharmacological activities exhibited by several identified compounds in Nigella sativa which allow a better understanding, and better elucidation, of the bioactive compounds responsible for the pharmacological effects. Also shown are the existence of other bioactive compounds that are still unexplored and could be of great interest. This review could be taken as a guide for future studies in the field.

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Section: Pharmacological Properties Of Nigella Sativamentioning

confidence: 99%