2019
DOI: 10.15570/actaapa.2019.46
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Cited by 2 publications
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“…Instead of neutralizing Dengue virus, these antibodies bind to the viral proteins in such a way that actually helps them to invade the immune system and further spread. 3,4 Another subtype of heterotypic antibodies is produced which act as the infamous Trojan horse of Troy. 3 These antibodies are non-neutralizing and are delivered to antigen-presenting cells (APCs) where they undergo aberrative processing after phagocytosis leading to high virion production, while surpassing the immunosurveillance.…”
Section: Sars-cov-2 and Trojan Horse Phenomenon-caveat In Vaccine Quest?mentioning
confidence: 99%
“…Instead of neutralizing Dengue virus, these antibodies bind to the viral proteins in such a way that actually helps them to invade the immune system and further spread. 3,4 Another subtype of heterotypic antibodies is produced which act as the infamous Trojan horse of Troy. 3 These antibodies are non-neutralizing and are delivered to antigen-presenting cells (APCs) where they undergo aberrative processing after phagocytosis leading to high virion production, while surpassing the immunosurveillance.…”
Section: Sars-cov-2 and Trojan Horse Phenomenon-caveat In Vaccine Quest?mentioning
confidence: 99%