Reply: Uterine artery embolization for severe symptomatic fibroids: effects on fertility and symptoms

Torre, Antoine; Paillusson, B.; Fain, V.; Labauge, Pierre; Pelage, J.P.

doi:10.1093/humrep/deu148

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…There is little agreement regarding fertility status following uterine fibroid embolization. [27][28][29][30] Approximations of fertility status post myomectomy are placed at 53.6-55.9%, 31 but fertility rates post-UFE have not yet been effectively quantified. Published studies have limitations and biases while predictive values may be inaccurate.…”

Section: Bjrmentioning

confidence: 99%

Pregnancy success and outcomes after uterine fibroid embolization: updated review of published literature

Ludwig

Huff

Shanahan

et al. 2019

The British Journal of Radiology

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Females with symptomatic leiomyomas (fibroids) wishing to maintain fertility are faced with difficult treatment choices. These include uterine fibroid embolization (UFE), myomectomy, hormonal therapy, MRI high intensity focused ultrasound, and myolysis. This review focuses on UFE, one of the most commonly accepted minimally invasive procedural choices among patients with symptomatic fibroids wishing to retain the option of becoming pregnant in the future, and makes comparisons to myomectomy which has historically been the surgical choice for fertility-preserving fibroid treatment. Pubmed and Google Scholar searches using keywords such as: uterine artery embolization, uterine fibroid embolization, pregnancy, complications, infertility were performed between Jan 1, 2019 and May 10, 2019. Publications were chosen based on their inclusion of information pertaining to fertility or pregnancy after UFE without being limited to single case reports. Randomized controlled trials comparing myomectomy and UFE are limited due to study size and confounding variables, but through registry data and familiarity with referring clinicians, UFE has gained wide acceptance. Healthy pregnancies following UFE have been sporadically reported but the actual fertility rate after UFE remains uncertain. Conversely, low birth weight, miscarriage and prematurity have been associated with UFE. Despite inherent risks of possible fertility issues after UFE, the procedure remains an option for females with clinically symptomatic fibroids who desire pregnancy. However, additional research regarding rates of conception and obstetrical risks of infertility following UFE is necessary.

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Section: Bjrmentioning

confidence: 99%

Pregnancy success and outcomes after uterine fibroid embolization: updated review of published literature

Ludwig

Huff

Shanahan

et al. 2019

The British Journal of Radiology

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“…The differences of material used might put an impact on both uterine embolization and fertility. 8 Obstetrical hemorrhage is the leading cause of maternal mortality. After mother's health is out of danger, yet if persistent bleeding is observed, the main goal is for stopping hemorrhage, at the same time preserving the uterus.…”

Section: Introductionmentioning

confidence: 99%

Management of obstetric hemorrhage; an observational study highlighting the efficacy of uterine artery ligation

Ghouri

Mushtaq²,

Ahmed

et al. 2020

Int J Res Med Sci

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Background: Obstetrical hemorrhage is leading cause of maternal mortality. UAE is termed safe and effective method for resolving hemorrhage. objective of this study was to determine efficacy of uterine artery ligation in management of obstetrical hemorrhage.Methods: This cross sectional observational using non-probability convenient sampling technique was carried out for six months. After ethical approval, females between 18 to 35 years diagnosed with obstetrical hemorrhage, uterine atony refractory to medical treatment, having active bleeding from placental side or having normal coagulation profile were while females with post-partum hemorrhage because of retained products of conception, due to genital tract trauma or with disseminated intravascular coagulation were excluded. Analysis of data was done using SPSS version 23.0. Quantitative variables were reported as mean and standard deviation and for qualitative variables, frequency and percentages. Chi-square test was applied keeping p-value of <0.05 as statistically significant.Results: From 109 females with mean age 47±5.25 years. In comparison of parity distribution, 62 (56.88%) were multiparous and 47 (43.12%) were primiparous. Type of bleeding observed was antepartum 36(33.03%), peripartum 39 (35.78%) and postpartum in 34 (31.19%). Efficacy of uterine artery ligation in management of obstetric hemorrhage was observed to be 35 (32.11%). The efficacy of uterine artery ligation in management of obstetric hemorrhage in three categories of age groups reported significant association (p=0.0005) and type of bleeding (p=0.025).Conclusions: Efficacy of UAE in different types of obstetrical hemorrhage reported in our study was lower than expected in about one-third of females.

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Fertility after uterine artery embolization for symptomatic multiple fibroids with no other infertility factors

et al. 2016

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Reply: Uterine artery embolization for severe symptomatic fibroids: effects on fertility and symptoms

Cited by 3 publications

References 5 publications

Pregnancy success and outcomes after uterine fibroid embolization: updated review of published literature

Pregnancy success and outcomes after uterine fibroid embolization: updated review of published literature

Management of obstetric hemorrhage; an observational study highlighting the efficacy of uterine artery ligation

Fertility after uterine artery embolization for symptomatic multiple fibroids with no other infertility factors

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