Report of a Case Showing Congenital Defects, Short Stature, Retarded Sexual Development and No Urinary Gonadotropins

The Symmetrical Form of Status Bonnevie-Ullrich (Turner's Syndrome)

“…Numerous similar cases have since been reported by others (Sharpey-Schafer, 1941;Albright et al, 1942;Varney et al, 1942;Wilkins and Fleischmann, 1944;Lisser et al, 1947;Del Castillo et al, 1947;Dorff et al, 1947;Jackson, 1950;Jackson and Sougin-Mibashan, 1953). Congenital anomalies observed by these authors, in addition to the webbed neck, cubitus valgus, and short stature emphasized by Turner, included the low hair-line at the nape of the neck, dystrophies of the ears, " shield " chest, arched palate, scoliosis of the spine, and coarctation of the aorta.…”

“…However, the term " syndrome of ovarian agenesis " is even more unsatisfactory, as the condition has been 'observed, though less commonly, in males (Flavell, 1943;Dorff et al, 1948;McCullagh, 1948;Greenblatt and Nieburgs, 1948;Reforzo-Membrives et at:, 1949;Sohval, 1951;Cunningham and Harley, 1951;James, 1952;Sougin-Mibashan and Jackson, 1953;Mackenzie, 1953). It is possible that the term " Bonnevie-Ullrich-Turner syndrome," as suggested by James (1952), would do most to clarify the present somewhat disjointed situation and combine the contributions to the subject from both the Continental and the English language literature.…”

Gonadal Dysgenesis: Modern Concepts

“…In the present series, five adult cases did not have increased levels. Several other workers have reported similar results (Dorff et al, 1947;Hertz et al, 1950;Sternlieb et al, 1954;Carpentier et al, 1956). In a separate paper (Jackson and Hoffenberg, 1956) (Albert, 1956 The effect of cortisone and corticotrophin on urinary F.S.H.…”

Two Cases of Gonadal Dysgenesis with Typical Female Chromosomal Pattern

“…The problems of gonadotropin de term inations, which are partly due to the lability of the compounds and partly to the lim itation of bioessays, m ay account for the discrepancies. On the other hand, absence or low gonadotropin ex cretion in patients with gonadal dysgenesis have been reported [13,36].…”