Report of the nomenclature committee and the 1989 catalog of mapped genes (Part 1 of 3)

McAlpine, P.J.; Shows, T.B.; Boucheix, Claude; Stranc, L.C.; Berent, Theresa; Pakstis, Andrew J.; Doute, R.C.

doi:10.1159/000132780

Cited by 57 publications

(13 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Two major barriers to the expedient integration of data are the lack of a flexible, universal nomenclature, and the variety of mapping resolutions associated with these data items. Even though a rigorous nomenclature exists for genes and mapped segments of DNA (59)(60)(61), this nomenclature has only limited usage outside the human gene mapping community and its scope is still too limited to accommodate more general "loci," such as contigs, YACs, and other objects arising in physical mapping. In addition, official names and symbols are often assigned only after initial publication under very different names.…”

Section: Discussionmentioning

confidence: 99%

Mapping the Human Genome: Current Status

Stephens

Cavanaugh

Gradie

et al. 1990

Science

View full text Add to dashboard Cite

The human genome has already been the subject of extensive research activity even though the Human Genome Project is only just officially starting. This review and the accompanying wall chart attempt to provide an integrated, quantitative, and detailed summary of the status of knowledge on the human genome in mid-1990. The analysis has highlighted the rudimentary nature of many of the information links needed for the task. While this overview could not be fully comprehensive and required simplifying assumptions, the results have provided estimates of relative progress on a region-by-region basis throughout the genome.

show abstract

Section: Discussionmentioning

confidence: 99%

Mapping the Human Genome: Current Status

Stephens

Cavanaugh

Gradie

et al. 1990

Science

View full text Add to dashboard Cite

show abstract

“…At the 1989 human gene mapping conference the genes for seven different cytoplasmic aminoacyl-tRNA synthetases have been assigned to human chromosomal loci (McAlpine et al 1989). In addition, it has been reported that the gene for arginyl-tRNA synthetase may be located on chromosome 5 [S. M. Arfin, L. R. Carlock, S. C. Gerken, and J. J.…”

Section: Discussionmentioning

confidence: 99%

The human QARS locus: assignment of the human gene for glutaminyl-tRNA synthetase to chromosome 1q32?42

et al. 1990

View full text Add to dashboard Cite

We have used a cDNA encoding the core region of the human glutaminyl-tRNA synthetase to determine the chromosomal localization of the corresponding gene. Southern blots of restricted DNA from a panel of rodent-human cell lines and in situ chromosome hybridization gave identical results showing that the human gene locus for glutaminyl-tRNA synthetase resides on the distal long arm of chromosome 1. There are now nine mapped aminoacyl-tRNA synthetase genes in the human genome.

show abstract

“…The chromosomal distribution pattern of pJU78-related sequences was highly reminiscent of that of the argininosuccinate synthetase (ASS) gene and processed pseudogene family (McAlpine et al 1989), but no sequence homology was found.…”

Section: Chromosomal Allocation Of Pju78 Family Membersmentioning

confidence: 99%

A novel human multi-locus DNA family detected by pJU78 (DF31)

et al. 1991

View full text Add to dashboard Cite

pJU78 is a 2.9-kb cloned human DNA segment derived from Xq24-q26. When used as a hybridization probe, it detects some 25 related sequences dispersed over the genome, including several autosomes and the X and Y chromosomes. Several pJU78-related sequences were chromosomally allocated and five different restriction fragment length polymorphisms detected and partially characterized in population and family studies. This sequence family was not found in non-primate species. The sequence appears to lack CpG-island character and is not detectably expressed in a variety of human tissues.

show abstract

Report of the nomenclature committee and the 1989 catalog of mapped genes (Part 1 of 3)

Cited by 57 publications

References 0 publications

Mapping the Human Genome: Current Status

Mapping the Human Genome: Current Status

The human QARS locus: assignment of the human gene for glutaminyl-tRNA synthetase to chromosome 1q32?42

A novel human multi-locus DNA family detected by pJU78 (DF31)

Contact Info

Product

Resources

About