1997
DOI: 10.1001/jama.1997.03550060053031
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Reporting Institutional Review Board Approval and Patient Consent

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“…Ten cadaver heads (Innoved Institute, Inc, Bensenville, Illinois, USA) were used according to the Helsinki guidelines. 8 Bilateral rinses of the sinonasal cavity were performed using a “labeling solution” that contained a final concentration of 0.1% methylene blue hydrate endoscopically visible tracer (Sigma Aldrich, St Louis, Missouri, USA) and 8.6% iothalamate meglumine radio-opaque contrast agent (Mallinkrodt Inc., St Louis, Missouri, USA) combined in 0.9% premixed saline (Becton-Dickinson, Franklin Lakes, New Jersey, USA). Labeling solution (240 mL volume) was irrigated through each nostril of the cadaver using a NeilMed sinus rinse bottle (NeilMed Pharmaceuticals, Santa Rosa, California, USA), with each head inclined forward 20° to mimic standard patient positioning when performing nasal irrigations.…”
Section: Methodsmentioning
confidence: 99%
“…Ten cadaver heads (Innoved Institute, Inc, Bensenville, Illinois, USA) were used according to the Helsinki guidelines. 8 Bilateral rinses of the sinonasal cavity were performed using a “labeling solution” that contained a final concentration of 0.1% methylene blue hydrate endoscopically visible tracer (Sigma Aldrich, St Louis, Missouri, USA) and 8.6% iothalamate meglumine radio-opaque contrast agent (Mallinkrodt Inc., St Louis, Missouri, USA) combined in 0.9% premixed saline (Becton-Dickinson, Franklin Lakes, New Jersey, USA). Labeling solution (240 mL volume) was irrigated through each nostril of the cadaver using a NeilMed sinus rinse bottle (NeilMed Pharmaceuticals, Santa Rosa, California, USA), with each head inclined forward 20° to mimic standard patient positioning when performing nasal irrigations.…”
Section: Methodsmentioning
confidence: 99%