Repository Penicillin Therapy of Pinta in the Mexican Peasant

Treatment of Early Venereal Syphilis with Antibiotics

“…Although less easy to administer than procaine penicillin, this preparation has proved to be the natural successor to penicillin in oil-beeswax and is now the most widely used throughout the world, not only for venereal syphilis but also for endemic syphilis and the other treponematoses, yaws and pinta (see Langer and Kruger, 1952;Gay Prieto, Alvares Cascos, and Orusco, 1953;Vilanova and Alvarado, 1953;Cutler, Olansky, and Price, 1955, for venereal syphilis: Murray, Merriweather, and Freedman, 1956;Grin, 1956, for endemic syphilis: Hackett and Guthe, 1956;Samame, 1956;Zahra, 1956;Soetopo, Wasito, Soedarsono, and Tjokrodipo, 1956;Hume andFacio, 1956, for yaws: andRein, Kitchen, Marquez, andVarela, 1952, for pinta: see also Guthe and Willcox, 1954).…”

Treatment of Early Venereal Syphilis with Antibiotics

“…In Aqueous Suspension.-The discovery by Buckwalter and Dickison (1948) Although less easy to administer than procaine penicillin, this preparation has proved to be the natural successor to penicillin in oil-beeswax and is now the most widely used throughout the world, not only for venereal syphilis but also for endemic syphilis and the other treponematoses, yaws and pinta (see Langer and Kruger, 1952;Gay Prieto, Alvares Cascos, and Orusco, 1953;Vilanova and Alvarado, 1953;Cutler, Olansky, and Price, 1955, for venereal syphilis: Murray, Merriweather, and Freedman, 1956;Grin, 1956, for endemic syphilis: Hackett and Guthe, 1956;Samame, 1956;Zahra, 1956;Soetopo, Wasito, Soedarsono, and Tjokrodipo, 1956;Hume andFacio, 1956, for yaws: andRein, Kitchen, Marquez, andVarela, 1952, for pinta: see also Guthe and Willcox, 1954).…”

Changing patterns of treponemal disease.

“…The understanding of this disease owes much to the pioneering work of Herrejon (1938) and later of Varela and others in Mexico (Rein, Kitchen, Marquez, and Varela, 1952); Guimaraes, Rodriquez, Costa, Silva, and Padilha Goncalves in Brazil; Leon Blanco in Cuba; and Sainz in Ecuador.…”