Representative sample survey on factors determining the Czech physicians’ awareness of generic drugs and substitution

Malý, Josef; Zimcikova, Eva; Babica, Jan; Kubêna, Aleŝ; Kostřiba, Jan

doi:10.1186/s12913-019-4631-y

Cited by 3 publications

(3 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A Czech study by Maly et al specifically asked about equivalence; 60.4% of physicians acknowledged the equivalence of generic and original products [ 16 ]. In the present study from Vienna, 70.2% of physicians agreed with the equivalence.…”

Section: Discussionmentioning

confidence: 99%

“…Respectively, in Vienna, that figure is 16.3%. Compared to the study by Maly et al, more than twice as many Viennese physicians have had poor experiences with generic drugs in the clinic as their colleagues from the Czech Republic (9.9% versus 4.4%) [ 16 ].…”

Section: Discussionmentioning

confidence: 99%

“…Several international publications also support the finding of our study on the influence of background knowledge on personal attitudes toward generic drugs. Significant correlation analyses have also been conducted by Maly et al and Domeyer et al [ 16 , 17 ].…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Perception of pharmacological equivalence of generics or biosimilars in healthcare professionals in Vienna

Binder,

Zeitlinger

2023

Eur J Clin Pharmacol

View full text Add to dashboard Cite

Purpose Due to constantly rising therapy costs, biosimilars and generic drugs have gained tremendous importance through recent decades. Nevertheless, the acceptance among healthcare workers regarding biosimilars and generic drugs in previously published international studies is considerably lower than the scientific data on equivalent safety and efficacy would suggest. The aim of this questionnaire-based survey was to determine the perception and knowledge regarding generic drugs and biosimilars by medical professionals from different healthcare facilities in Vienna, Austria. Methods The online questionnaire was sent to public and religious hospitals in Vienna, including the university hospital “Vienna General Hospital.” In addition, doctors’ offices were reached by sending out the questionnaire in the weekly news of the Vienna Medical Association. Results A total of 282 physicians and 311 graduated nurses took part in the study. 63% and 62% of the participants were convinced that generic respective biosimilar drugs were clinically equivalent to the original reference drug. On average, 1.6 out of 4 knowledge questions were answered correctly about generics, while only 0.87 out of 4 questions were answered accurately about biosimilars. Conclusion The results of this study support the outcome from previous surveys demonstrating that a large proportion of healthcare professionals is still skeptical about generics and biosimilars. According to the results of this study, better education of the medical staff might ensure greater acceptance of these types of drugs.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Perception of pharmacological equivalence of generics or biosimilars in healthcare professionals in Vienna

Binder,

Zeitlinger

2023

Eur J Clin Pharmacol

View full text Add to dashboard Cite

show abstract

Prescription writing pattern among the dental practitioners of a tertiary care hospital in Karachi

Shah,

Alam,

Minallah

et al. 2024

BMC Prim. Care

View full text Add to dashboard Cite

Objective To identify the frequency and types of prescription errors, assess adherence to WHO prescribing indicators, and highlight the gaps in current prescribing practices of Junior dental practitioners in a tertiary care hospital in Karachi, Pakistan. Methods This cross-sectional study was conducted from January 2021 to March 2021. The study included the prescriptions by house surgeons and junior postgraduate medical trainees for walk-in patients visiting the dental outpatient department. A total of 466 prescriptions were evaluated for WHO core drug prescribing indicators. The prescription error parameters were prepared by studying the WHO practical manual on guide to good prescribing and previous studies. Prescription errors, including errors of omission related to the physician and the patients, along with errors of omission related to the drug, were also noted. The statistical analysis was performed with SPSS version 25. Descriptive analysis was performed for qualitative variables in the study. Results The average number of drugs per encounter was found to be 3.378 drugs per prescription. The percentage of encounters with antibiotics was 96.99%. Strikingly, only 16.95% of the drugs were prescribed by generic names and 23.55% of drugs belonged to the essential drug list. The majority lacked valuable information related to the prescriber, patient, and drugs. Such as contact details 419 (89.9%), date 261 (56%), medical license number 466 (100%), diagnosis 409 (87.8%), age and address of patient 453 (97.2%), form and route of drug 14 (3%), missing drug strength 69 (14.8%), missing frequency 126 (27%) and duration of treatment 72 (15.4%). Moreover, the wrong drug dosage was prescribed by 89 (19%) prescribers followed by the wrong drug in 52 (11.1%), wrong strength in 43 (9.2%) and wrong form in 9 (1.9%). Out of 1575 medicines prescribed in 466 prescriptions, 426 (27.04%) drug interactions were found and 299 (64%) had illegible handwriting. Conclusion The study revealed that the prescription writing practices among junior dental practitioners are below optimum standards. The average number of drugs per encounter was high, with a significant percentage of encounters involving antibiotics. However, a low percentage of drugs were prescribed by generic name and from the essential drug list. Numerous prescription errors, both omissions and commissions, were identified, highlighting the need for improved training and adherence to WHO guidelines on good prescribing practices. Implementing targeted educational programs and stricter regulatory measures could enhance the quality of prescriptions and overall patient safety.

show abstract

Shaping of the evidence-based substitution conceptual framework of the original medicines to generic counterparts in Ukraine

Dobrova

Popov

Зупанец

et al. 2021

SR: PS

View full text Add to dashboard Cite

The aim. To develop conceptual framework of the strategy for a reasonable transition from original to generic medicines by complex implementation of proper bioequivalence studies and sufficient therapeutic drug monitoring management. Materials and methods. To conduct the study, we used the lists of medicines included in the state reimbursement program “Dostupny Liky” (Affordable Medicines), and materials of reports on medicines public procurement provided on the website of the Ministry of Health of Ukraine and the National Health Service of Ukraine, as well as information data on the results of studies of the quality and effectiveness of these drugs provided by the Rx-Index website. In the course of the study, the methods of logical analysis, SWOT analysis, and statistical evaluation of results, Kingdon’s Policy Streams Approach and the method of flowcharts construction were used. The concept of evidence-based medicine substitution formation in Ukraine was designed applying the Policy Streams Approach. Results. The analysis of public procurement programs for drugs for the period 2018–2020, as well as the analysis of drugs included in the new list under the “Dostupny Liky” (Affordable Medicines) program, carried out in the course of the study, showed that the level of evidence of data on assessing their effectiveness remains low. At the same time, more than 1.5 billion UAH (~ 50 mln USD) is spent annually on the purchase of such drugs and reimbursement of their cost, and the question of the optimal selection and monitoring of pharmacotherapy with these drugs remains open. A structural model has been developed, in which three basic levels are identified: provision of regulatory and financial components, executive and the level of implementation of the results. The SWOT-analysis of the strengths and weaknesses, as well as external opportunities and threats for the implementation of the conceptual framework made it possible to substantiate the advantages and reveal the possibilities of attracting clinical centers of universities and research institutions to the implementation of the concept. A framework for the interaction of a research center with health care institutions in the implementation of therapeutic drug monitoring was developed for low-income and low-middle income countries on the example of Ukraine. Distribution of responsibilities was proposed and the basic principles of interaction between performers of therapeutic drug monitoring were highlighted. Conclusions. Based on the results of the analysis of the evidence of the quality and effectiveness of drugs included in public procurement and in reimbursement programs, the key problems of organizing pharmaceutical provision of an appropriate level of quality for a number of chronic diseases requiring lifelong therapy were identified. The conceptual framework of evidence-based original medicines substitution to generic counterparts have been formed; and the ways of its implementation in the conditions of scarce financial resources on the example of Ukraine have been substantiated

show abstract

Representative sample survey on factors determining the Czech physicians’ awareness of generic drugs and substitution

Cited by 3 publications

References 31 publications

Perception of pharmacological equivalence of generics or biosimilars in healthcare professionals in Vienna

Perception of pharmacological equivalence of generics or biosimilars in healthcare professionals in Vienna

Prescription writing pattern among the dental practitioners of a tertiary care hospital in Karachi

Shaping of the evidence-based substitution conceptual framework of the original medicines to generic counterparts in Ukraine

Contact Info

Product

Resources

About