Reproducibility of masked hypertension and office-based hypertension: a systematic review and meta-analysis

Antza, Christina; Farmakis, Ioannis; Doundoulakis, Ioannis; Akrivos, Evangelos; Stalikas, Nikolaos; Zafeiropoulos, Stefanos; Kostopoulos, Georgios; Stabouli, Stella; Giannakoulas, George; Kotsis, V.

doi:10.1097/hjh.0000000000003111

Cited by 8 publications

(7 citation statements)

References 29 publications

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“…An increase in risk of CV and kidney events has also been observed in diabetic patients with MH, especially when the BP elevation occurs during the night [835]. A systematic review and meta-analysis has shown a slight to fair reproducibility of MH that was better for ABPM than for HBPM [836], while a limited reproducibility has been reported in other studies [62]. Thus, the diagnosis of MH requires confirmation with at least a second set of office and out-of-office BP measurements.…”

Section: Specific Hypertension Phenotypesmentioning

confidence: 99%

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension

Chairperson

Co-Chair

Brunström

et al. 2023

Journal of Hypertension

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Document Reviewers: Luis Alcocer (Mexico), Christina Antza (Greece), Mustafa Arici (Turkey), Eduardo Barbosa (Brazil), Adel Berbari (Lebanon), Luís Bronze (Portugal), John Chalmers (Australia), Tine De Backer (Belgium), Alejandro de la Sierra (Spain), Kyriakos Dimitriadis (Greece), Dorota Drozdz (Poland), Béatrice Duly-Bouhanick (France), Brent M. Egan (USA), Serap Erdine (Turkey), Claudio Ferri (Italy), Slavomira Filipova (Slovak Republic), Anthony Heagerty (UK), Michael Hecht Olsen (Denmark), Dagmara Hering (Poland), Sang Hyun Ihm (South Korea), Uday Jadhav (India), Manolis Kallistratos (Greece), Kazuomi Kario (Japan), Vasilios Kotsis (Greece), Adi Leiba (Israel), Patricio López-Jaramillo (Colombia), Hans-Peter Marti (Norway), Terry McCormack (UK), Paolo Mulatero (Italy), Dike B. Ojji (Nigeria), Sungha Park (South Korea), Priit Pauklin (Estonia), Sabine Perl (Austria), Arman Postadzhian (Bulgaria), Aleksander Prejbisz (Poland), Venkata Ram (India), Ramiro Sanchez (Argentina), Markus Schlaich (Australia), Alta Schutte (Australia), Cristina Sierra (Spain), Sekib Sokolovic (Bosnia and Herzegovina), Jonas Spaak (Sweden), Dimitrios Terentes-Printzios (Greece), Bruno Trimarco (Italy), Thomas Unger (The Netherlands), Bert-Jan van den Born (The Netherlands), Anna Vachulova (Slovak Republic), Agostino Virdis (Italy), Jiguang Wang (China), Ulrich Wenzel (Germany), Paul Whelton (USA), Jiri Widimsky (Czech Republic), Jacek Wolf (Poland), Grégoire Wuerzner (Switzerland), Eugene Yang (USA), Yuqing Zhang (China).

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Section: Specific Hypertension Phenotypesmentioning

confidence: 99%

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension

Chairperson

Co-Chair

Brunström

et al. 2023

Journal of Hypertension

Self Cite

1,126

280

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“…This is possibly attributed to the high proportion of normotension (73.9% were normotensives in the untreated participants). A previous meta-analysis reported a similar κ-value (0.39) regarding hypertension phenotype reproducibility based on home BP in untreated individuals 21 . This meta-analysis included the studies conducted within 1 week or half a year 21 .…”

Section: Discussionmentioning

confidence: 55%

“…A previous meta-analysis reported a similar κ-value (0.39) regarding hypertension phenotype reproducibility based on home BP in untreated individuals 21 . This meta-analysis included the studies conducted within 1 week or half a year 21 . Therefore, the hypertension phenotype reproducibility appeared not to be good regardless of the measurement interval.…”

Section: Discussionmentioning

confidence: 55%

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The long-term reproducibility of the white-coat effect on blood pressure as a continuous variable from the Ohasama Study

Satoh

Yoshida

Metoki

et al. 2023

Sci Rep

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There is little information about the reproducibility of the white coat effect, which was treated as a continuous variable. To investigate a long-term interval reproducibility of the white-coat effect as a continuous variable. We selected 153 participants without antihypertensive treatment (men, 22.9%; age, 64.4 years) from the general population of Ohasama, Japan, to assess the repeatedly measured white-coat effect (the difference between blood pressures at the office and home) in a 4-year interval. The reproducibility was assessed by testing the intraclass correlation coefficient (two-way random effect model-single measures). The white-coat effect for systolic/diastolic blood pressure slightly decreased by 0.17/1.56 mmHg at the 4-year visit on average. The Bland–Altman plots showed no significant systemic error for the white-coat effects (P ≥ 0.24). The intraclass correlation coefficient (95% confidence interval) of the white-coat effect for systolic blood pressure, office systolic blood pressure, and home systolic blood pressure were 0.41 (0.27–0.53), 0.64 (0.52–0.74), and 0.74 (0.47–0.86), respectively. Change in the white-coat effect was mainly affected by a change in office blood pressure. Long-term reproducibility of the white-coat effect is limited in the general population without antihypertensive treatment. The change in the white-coat effect is mainly caused by office blood pressure variation.

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“…Although, many guidelines consider ABPM as the reference standard, it is undeniable that home BP monitoring represents an important tool for MH screening due to the limited availability and cost of ABPM in many healthcare systems [1,9]. Data on short-and long-term reproducibility of MH diagnosis are scarce and evidence has been accumulated in favor of a limited reproducibility of this phenotype over time [10,11].…”

Section: Introductionmentioning

confidence: 99%

Unmasking left ventricular systolic dysfunction in masked hypertension: looking at myocardial strain. A review and meta-analysis

Cuspidi

Gherbesi

Faggiano

et al. 2022

Journal of Hypertension

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Background and Aim:A growing body of evidence supports the view that masked hypertension (MH) (i.e. normal office and elevated out-of-office BP) is a blood pressure (BP) phenotype associated with increased risk of subclinical organ damage, cardiovascular disease and death as compared to true normotension. Whether left ventricular (LV) systolic function is impaired in individuals with MH is still a poorly defined topic. Therefore, we aimed to provide a new piece of information on LV systolic dysfunction in the untreated MH setting, focusing on speckle tracking echocardiography (STE) studies investigating LV global longitudinal strain (GLS), a more sensitive index of systolic function than conventional LV ejection fraction (LVEF).Methods:A computerized search was performed using Pub-Med, OVID, EMBASE and Cochrane library databases from inception until June 30, 2022. Full articles reporting data on LV GLS in MH, as assessed by ambulatory BP monitoring (ABPM), and normotensive controls were considered suitable for the purposes of review and meta-analysis.Results:A total of 329 untreated individuals with MH and 376 normotensive controls were included in six studies. While pooled average LVEF was not different between groups [64.5 ± 1.5 and 64.5 ± 1.3%, respectively, standard means difference (SMD): −0.002 ± 0.08, confidence interval (CI): 0.15/−0.15, P = 0.98), LV GLS was worse in MH patients than in normotensive counterparts (−18.5 ± 0.70 vs. −20.0 ± 0.34%, SMD: 0.68 ± 0.28, CI: 0.12/1.24, P < 0.01).Conclusions:Our findings suggest that early changes in LV systolic function not detectable by conventional echocardiography in the MH setting can be unmasked by STE and that its implementation of STE in current practice may improve the detection of subclinical organ damage of adverse prognostic significance.

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Reproducibility of masked hypertension and office-based hypertension: a systematic review and meta-analysis

Abstract: Impact of early glomerular fi ltration rate decline in response to antihypertensive treatment on risk of end-stage kidney disease and cardiovascular outcomes: a systematic review and meta-analysis: Erratum

Cited by 8 publications

References 29 publications

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension

2023 ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Hypertension

The long-term reproducibility of the white-coat effect on blood pressure as a continuous variable from the Ohasama Study

Unmasking left ventricular systolic dysfunction in masked hypertension: looking at myocardial strain. A review and meta-analysis

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