Reproductive and oncologic outcomes in women with non-epithelial ovarian cancer: Single center experience over 25 years

Sağnıç, Saliha; Karadağ, Ceyda; Tuncer, Hasan Aykut; Doğan, Selen; Şimşek, Tayup

doi:10.4274/tjod.galenos.2023.98036

Cited by 3 publications

(2 citation statements)

References 55 publications

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“…This group of ovarian cancers includes various subtypes, including dysgerminoma, yolk sac tumors, embryonal carcinoma, non-gestational choriocarcinoma, mixed germ cell tumors, and immature teratomas, each with distinct characteristics [3][4][5]. Dysgerminoma, akin to male seminoma, represents the most prevalent histological variant and immature teratoma and is associated with relatively high bilaterality rates [4,6,7].…”

Section: Introductionmentioning

confidence: 99%

Spontaneous Pregnancy After Fertility-Sparing Surgery and Adjuvant Chemotherapy for Advanced Pure Dysgerminoma: A Case Report

Goc,

Kastrati

et al. 2024

Preprint

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Section: Introductionmentioning

confidence: 99%

Spontaneous Pregnancy After Fertility-Sparing Surgery and Adjuvant Chemotherapy for Advanced Pure Dysgerminoma: A Case Report

Goc,

Kastrati

et al. 2024

Preprint

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“…7 Dysgerminoma, akin to male seminoma, represents the most prevalent histological variant and immature teratoma and is associated with relatively high bilaterality rates. 5,8,9 Platinum-based chemotherapy regimens have proven effective in extending survival and preserving fertility. 1,10 Given the chemosensitivity of these tumor cells, fertilitysparing surgery (FSS) has become a preferred treatment approach, particularly in patients desiring to preserve their reproductive capability.…”

Section: Introductionmentioning

confidence: 99%

Spontaneous pregnancy after fertility‐sparing surgery and adjuvant chemotherapy for advanced pure dysgerminoma: A case report

Göç,

Kastrati

et al. 2024

Clinical Case Reports

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Key Clinical MessageFertility‐sparing surgery and appropriate adjuvant chemotherapy for advanced malignant ovarian germ cell tumors have excellent survival results and promising reproductive and obstetric outcomes.AbstractThis case report aims to demonstrate the potential feasibility and success of fertility‐sparing surgery (FSS) coupled with adjuvant chemotherapy in treating advanced malignant ovarian germ cell tumor (MOGCT), focusing on pure dysgerminoma, fertility, and achieving spontaneous pregnancy. The patient was a 23‐year‐old female who initially presented with complaints of abdominal distension and a palpable mass and was subsequently diagnosed with advanced MOGCT. The patient provided a complete clinical and radiological response to FSS with complete surgical staging and cisplatin‐based chemotherapy (bleomycin, etoposide, and cisplatin). Despite being diagnosed with advanced MOGCT and treated with FSS and adjuvant chemotherapy, she later experienced spontaneous pregnancy, giving birth to a healthy child. This case study demonstrated the potential for successful fertility preservation and pregnancy in advanced‐stage MOGCT patients treated with personalized treatment approaches. Nevertheless, a broader investigation is needed to understand the relevant complex dynamics and to ascertain whether FSS with adjuvant chemotherapy could be a reliable approach in treating advanced MOGCT.

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A huge abdominal tumor was pathologically diagnosed as the mixed germ-cell tumor

Peng

Bai

et al. 2023

Asian Journal of Surgery

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Reproductive and oncologic outcomes in women with non-epithelial ovarian cancer: Single center experience over 25 years

Cited by 3 publications

References 55 publications

Spontaneous Pregnancy After Fertility-Sparing Surgery and Adjuvant Chemotherapy for Advanced Pure Dysgerminoma: A Case Report

Spontaneous Pregnancy After Fertility-Sparing Surgery and Adjuvant Chemotherapy for Advanced Pure Dysgerminoma: A Case Report

Spontaneous pregnancy after fertility‐sparing surgery and adjuvant chemotherapy for advanced pure dysgerminoma: A case report

A huge abdominal tumor was pathologically diagnosed as the mixed germ-cell tumor

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