Rescue excimer laser angioplasty for treatment of critical limb ischemia

Topaz, On

doi:10.1002/ccd.20159

Cited by 6 publications

(1 citation statement)

References 16 publications

(17 reference statements)

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“…The shallow penetration depth of the UV pulses limits the speed at which the catheter can be advanced, and therefore ELA is a time-consuming endeavor by default. 40,41 The costs of the catheter, approximately $1500 per device, as well as the price of the laser unit make it a very expensive option.…”

Section: Cryoplastymentioning

confidence: 99%

Endovascular therapy for critical limb ischemia

Arain

White

2008

Vasc Med

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Chronic critical limb ischemia (CLI) occurs when arterial perfusion is reduced below a threshold level that results in rest pain and/or tissue breakdown in the lower extremities. Importantly, it is associated with high cardiovascular morbidity and mortality. Without prompt revascularization, CLI may result in loss of a limb (i.e. amputation) and/or life. The goal of endovascular therapy is the re-establishment of pulsatile, straight-line flow to the distal extremity. Percutaneous transluminal angioplasty (PTA) has been shown to be effective and safe in the setting of CLI, with limb salvage rates that compare favorably with surgical procedures. Stents are indicated for failed PTA, while adjunctive therapies such as lasers, thermal angioplasty and atherectomy devices lack data demonstrating improved efficacy compared with conventional lower extremity interventions. In addition to successful revascularization, the institution of lifestyle changes, atherosclerotic risk factor modification, and pharmacologic therapies are indicated to reduce cardiovascular morbidity and mortality.

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Section: Cryoplastymentioning

confidence: 99%