Nuclear power generation technology is obviously a safe and economical way of generating power in modern society. As the low temperature heat source, the condenser of the nuclear power technology condenses the steam into condensate water and then establishes a certain degree of vacuum at the exhaust port of the turbine. The operation of condenser is critical to the nuclear power generation technology. In this paper, the influences of the arrangement of tube bundles on the condenser of nuclear power generation technology were investigated. Three types of condensers, including the church window type, the centripetal type, and the UT type, were analyzed using Ansys Fluent software. The steam flow velocity distribution, air concentration distribution, temperature distribution, and heat transfer coefficient distribution were studied. Under specific design conditions, the flow velocity in the church window type was large, the exhaust air concentration was small, the maximum flow rate distribution was relatively reasonable, and the air concentration distribution was more concentrated. The performances of the centripetal type and the UT type were slightly worse, and the steam condensation was less. In contrast, the condensation of the church window type was large, the relative performance was high, and the heat transfer performance was better.