Information technology has been widely used in airport economic zone in the daily management of the enterprise and government. The use of it to build quality and technical supervision information platform can realize the quality and technical supervision of law enforcement electronic and informatization, achieve supervise management informatization, decision support intelligent, business process standardization and information exchange release automation. At first, this paper analyzes the business requirements and functional requirements of quality and technical supervision information platform, and then discuss the overall structure and network topology structure of the information platform, analyses the design and construction of the information platform, and finally discusses the main application system of the information platform. Platform application helps to enhance the institutionalization and standardization of quality and technical supervision, standardize the market economic order, improve product quality, engineering quality and service quality and enhance the international competitiveness of economic zone industry, enterprises and products.