Research on Functionalized Gadolinium Oxide Nanoparticles for MRI and THz Imaging

Cristian, Ciobanu Romeo; Schreiner, Thomas; Vasile, Drug; Stanciu, Gabriela Dumitriţa; Alexa-Stratulat, Teodora; Luca, Andrei; Mihai, Cosmin Teodor; Tamba, Bogdan Ionel; Ciortescu, Irina

doi:10.1109/icepe.2018.8559855

Cited by 4 publications

(4 citation statements)

References 6 publications

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“…• Another THz source includes the quadratic Frequency Difference Generation (FDG) process in nonlinear crystals. Some of the important THz emitters and detectors are electro-optical sources, photoconductive antennas, electronic sources, bolometers, pyroelectric, heterodyne mix receivers and Golay cells [46].…”

Section: A the Thz Radiation Sources And Detectorsmentioning

confidence: 99%

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Gezimati

Singh

2023

IEEE Access

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There is a keen interest in the exploration of new generation emitters and detectors due to advancements in innovation of new materials and device processing technologies which have opened up new frontiers in the Terahertz (THz) spectrum. Therefore, it is necessary to review the developments in THz technology for healthcare applications, their impact, implications and prospects for ongoing research and development. This paper provides a broad overview of the current status and prospects of application of THz imaging and sensing for the healthcare domain. We present current knowledge, identify existing challenges for wide scale clinical adoption of THz systems and prospective opinions to facilitate research and development towards optimized and miniaturized THz systems and biosensors that provide real operational convenience through emerging trends. Firstly, we provide an overview of the THz imaging and sensing techniques that exploit properties of THz generation and detection with emphasis on terahertz time domain spectroscopy (THz-TDS) and THz Metamaterials. The mechanisms of tissue image contrast and the application of THz imaging and sensing for biomedical applications in particular, the cancer detection application is reported. Secondly, an outlook toward the advancements in THz technology in the interface of healthcare 4.0 and its enabling technologies is explored for next generation smart and connected healthcare systems. Third, we identify the merits and existing challenges in THz cancer imaging and sensing and suggest prospective opinions to pave way to ongoing and future research. Further, we discuss the recent advances in THz imaging development and the contribution of near-field techniques based on plasmonic, and resonance based metasurfaces, waveguides etc. for breaking the diffraction limit towards development of THz systems that are convenient for point of care. We bring researchers a roadmap for future research scope.

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Section: A the Thz Radiation Sources And Detectorsmentioning

confidence: 99%

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Gezimati

Singh

2023

IEEE Access

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“…6 (a) (ⅰ)Schematic of GONPs -enhanced THz imaging [43] ; (ⅱ) THz absorption at various concentrations of GONPs [57] . (b) THz images of AGS cells containing different concentrations of GONPs [58] .…”

Section: Nano-contrast Agents For Thz Biomedical Imagingmentioning

confidence: 99%

“…The huge absorption difference made it perfectly suitable as a contrast agent for THz imaging (Figure 6a). Figure 6b indicates an enhanced THz imaging contrast for human gastric cancer cells (AGS) in culture assisted by the use of GONPs [58]. Bowman's group [59] proposed carbon-based nanoparticles as contrast agents.…”

Section: Nano-contrast Agents For Thz Biomedical Imagingmentioning

confidence: 99%

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Emergent progress in the interaction of terahertz wave and functional materials

An,

Yuan,

Tian

et al. 2022

TST

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Terahertz (THz) technology has attracted great attention for its application potential in next-generation communications, medical imaging, security, etc. The investigation on the interaction of THz wave and functional materials is the fundamental issues for exploring new physics in condensed matter and then developing advanced THz devices. This review elucidates some emergent work focusing on this point, including ultrafast phenomena studied using time-resolved THz spectroscopy, nanoparticles as contrast agents for THz medical imaging, and spintronics in THz range. The technical problems and research difficulties for present and future work are also presented. This review aims to afford researchers a better understanding of the different THz function materials and their applications.

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Terahertz technology in intraoperative neurodiagnostics: A review

Chernomyrdin¹,

Musina²,

Никитин³

et al. 2023

OEA

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Terahertz (THz) technology offers novel opportunities in biology and medicine, thanks to the unique features of THzwave interactions with tissues and cells. Among them, we particularly notice strong sensitivity of THz waves to the tissue water, as a medium for biochemical reactions and a main endogenous marker for THz spectroscopy and imaging. Tissues of the brain have an exceptionally high content of water. This factor, along with the features of the structural organization and biochemistry of neuronal and glial tissues, makes the brain an exciting subject to study in the THz range. In this paper, progress and prospects of THz technology in neurodiagnostics is overviewed, including diagnosis of neurodegenerative disease, myelin deficit, tumors of the central nervous system (with an emphasis on brain gliomas), and traumatic brain injuries. Fundamental and applied challenges in study of the THz-wave -brain tissue interactions and development of the THz biomedical tools and systems for neurodiagnostics are discussed.

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Research on Functionalized Gadolinium Oxide Nanoparticles for MRI and THz Imaging

Cited by 4 publications

References 6 publications

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Terahertz Imaging and Sensing for Healthcare: Current Status and Future Perspectives

Emergent progress in the interaction of terahertz wave and functional materials

Terahertz technology in intraoperative neurodiagnostics: A review

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