This paper takes the cruise passenger cabin as the research object, builds the virtual environment model according to the relevant theoretical knowledge and materials, introduces and studies the theory of ergonomic design evaluation, establishes the human-machine environment evaluation index system and comprehensive evaluation model of the cruise passenger cabin, introduces several common comprehensive evaluation methods, compares the advantages and disadvantages of different methods, and combines them with this design object so as to select the applicable evaluation method to evaluate the cabin design scheme. It also introduces several common comprehensive evaluation methods, compares the advantages and disadvantages of different methods, combines them with the design object, so as to select the applicable evaluation methods to evaluate the cabin design scheme and make the cabin design evaluation more systematic, accurate, and reasonable, realizes the three-dimensional visualization of the cruise ship cabin based on virtual reality technology and other technologies, and conducts the ergonomic evaluation of the design effect. The relevant knowledge involved includes human-machine-environment system engineering theory, 3D modeling theory, hierarchical analysis theory, fuzzy comprehensive evaluation theory, and virtual reality development theory. The concept of intelligent environment design is introduced into the environmental design of the intelligent entertainment system of cruise ships, and after the systematic study of the user’s demand level and cabin environment design element system, the problems existing in it are handled and combined with intelligent products, the different functions of intelligence are classified and studied, and the different forms of control are specifically studied to provide the basis for the subsequent specific design. In the case study, an overall evaluation of the architectural aesthetics of the target ship was derived through evaluation experiments. Based on the results, specific indicators at different levels can be traced, thus providing guidance directions for optimal design. The methods such as fuzzy synthesis evaluation and the idea of integrating the evaluation process with VR experience adopted in this paper can provide reference ideas for similar studies.