The ADDIE model is highly compatible with teaching in terms of educational purposes, concepts, and processes and has a positive contribution to teaching. In this study, the ADDIE model is used to teach a comprehensive practice course for automobile majors in order to promote the systematic design and implementation of teaching. In this paper, the main problems to be solved are firstly extracted through the elemental analysis of the comprehensive practice course system of automobile majors, and the expected level of learning objectives to be achieved is pre-set. Then, a complete integration of educational media resources is carried out to test the effectiveness of the developed course instructional design. The fuzzy evaluation model is utilized to assess the quality of the course constructed by the ADDIE model. Specifically, the hierarchical analysis method is applied to calculate the index weights, and then the entropy weight method is used to correct the obtained index weights to obtain the final weights, determine the fuzzy operator, and make a comprehensive assessment of the teaching quality. It can be seen through the analysis that the method proposed in this paper makes the average final grade of the experimental class higher than that of the control class by 3.4524 points, and the final rating of teaching quality obtained by the method of this paper using the fuzzy comprehensive evaluation model is 3.7968 points, which is a good level. This indicates that the upgraded method of teaching practical courses is more effective than the original method, enhances the overall performance of students, and fulfills the requirements for teaching practice in automotive specialties.