Research on the Squamous Cell Carcinoma of the Cervix uteri by Cytophotometric and Planimetric Evaluations

Cytophotometric Determination of DNA in Minimal Invasive Cancer of the Human Cervix uteri

“…When the cervix uteri is changing into cancerous tissue there are increased DNA values in the cell nuclei, leading to atypical histograms not only within the carcinoma itself, but already in precancerous stages [Sandritter andFischer, 1962\ Sandritter, 1964], In earlier investigations [Herzog, 1977] a carcinoma was accidentally found in situ, showing a wide range in the DNA histogram. On cutting the conus in serial steps and slides we found early invasion.…”

DNA Distribution Patterns of Preneoplastic Cells and Their Interpretation

“…The precancerous stages of the cervix uteri have been investigated thoroughly by means of cytology, histology and also cytophotometry [27][28][29] and their clinical importance is well known. Therefore, we have utilized these results as a model correlating DNA dis tribution patterns from stomach cells in the different pathologic stages to DNA distribution patterns from cervix cells in defined stages in order to obtain some information about the clinical value especially of the CAG.…”