Research output on Lavender, 2008–2012

Gul, Sumeer; Nisa, Nahida Tun; Shah, Tariq; Shah, Mohammad Umar Ali; Wani, Altaf Bashir

doi:10.1016/j.eujim.2015.05.004

Cited by 7 publications

(3 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[7,8] The multi-target characteristics may be surpassing single-target drugs in the treatment of complex diseases. [9] Lavandula angustifolia (LA) is an aromatic plant belongs to the family of Labiatae, [10,11] and now extending throughout Spain, France, China, North-East Italy. [12] Lavender is traditionally used to treat encephalopathy in Xinjiang, China.…”

Section: Introductionmentioning

confidence: 99%

Integrating Zebrafish Model to Screen Active Ingredients and Network Pharmacology Methods to Explore the Mechanism of Lavandula angustifolia Therapy for Alzheimer's Disease

Cao

Yan

et al. 2022

ChemistrySelect

View full text Add to dashboard Cite

Lavandula angustifolia (LA) is a traditional Chinese herbal medicine commonly used as a folk medicine to treat brain diseases; in previous pharmacological studies, its water extract has been reported to have neuroprotective effects with the potential to be used in the treatment of Alzheimer's disease (AD). However, the material basis and the action mechanism of the effects were not clear. Hence, we have adopted a fast, low‐cost strategy to address this problem, through the following three processes: degreased lavender flower grains are extracted stepwise, main active sites are screened by zebrafish AD model, and key compounds and major pathways are identified using network pharmacology tools. The initial results show luteolin‐7‐glucoside, Apigenin‐7‐O‐glucoside, Salvianolic acid A and Rosmarinic acid can be used as the main active ingredient for lavender treatment of Alzheimer's disease. The major biological processes involved in these compounds include regulation of defense responses, decomposition of extracellular matrix, oxidative stress response, and peptidyl tyrosine phosphorylation. The most important metabolic pathways are cancer, IL‐17 signaling and age‐rage signaling indiabetic complications. Therefore, the strategies developed in this study are helpful to address the unclear material basis and mechanism of the effect of Chinese herbal medicine as well as form a bridge between traditional Chinese herbal medicine and modern medical language.

show abstract

Section: Introductionmentioning

confidence: 99%

Integrating Zebrafish Model to Screen Active Ingredients and Network Pharmacology Methods to Explore the Mechanism of Lavandula angustifolia Therapy for Alzheimer's Disease

Cao

Yan

et al. 2022

ChemistrySelect

View full text Add to dashboard Cite

show abstract

“…They are aromatic plants of great economic importance due to their uses in several industry branches (pharmaceutical, food, cosmetics, perfumery and aromatherapy), particularly Lavandula angustifolia (fine lavender), Lavandula x intermedia (lavandin), Lavandula latifolia (spike lavender) and Lavandula stoechas (Spanish lavender) [1][2][3][4]. Since ancient times lavender has been used to perfume bathing water to help purify the body and spirit; and to alleviate insomnia; anxiety; fatigue; meteorism; flatulence; vomiting; loss of appetite; headaches; toothaches; joint pain and sores [5]. These properties have been attributed to its essential oils (EOs), nevertheless some authors in their systematic review and meta-analysis that have focused on the effect of lavender EOs in humans concluded that more attention should be paid in the interpretation of results due to the following factors: heterogeneity between studies, small number of studies and small sample sizes [6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Essential oils of spontaneous species of the genus Lavandula from Portugal: a brief review

Vairinhos

Miguel

2020

Zeitschrift Für Naturforschung C

View full text Add to dashboard Cite

Spontaneous lavender growing in uncultivated fields in Portugal have been used in traditional medicine for internal and external uses. The essential oils (EOs) of Lavandula stoechas subsp. luisieri are characterized by the presence of trans-α-necrodyl acetate and trans-necrodol. These EOs are able to prevent the generation and deposition of neurotoxic β-amyloid peptide in Alzheimer’s disease. The EOs also present antibacterial, anti-fungal, anti-Leishmania, antioxidant, anti-inflammatory and antifeedant effects. In the case of hydrodistillation, the predominant compound of Lavandula viridis EO was 1,8-cineole, nevertheless in the case of supercritical fluid extraction, the main constituent was camphor. In in vitro shoots EOs, 1,8-cineole and α-pinene were the most important compounds. The EOs presented anti-fungal activity particularly against Cryptococcus neoformans and dermatophytes. The antioxidant and anti-protozoal activities of L. viridis EOs were lower than L. stoechas subsp. luisieri EOs, with hydrodistillation being the best method for obtaining samples with higher antioxidant and anti-acetylcholinesterase activities. The presence of fenchone, 1,8-cineole and camphor was a common trace of the Lavandula pedunculata subsp. pedunculata EOs and in in vitro axillary shoots EOs. Lavandula pedunculata subsp. lusitanica EOs were predominantly constituted of fenchone and camphor. The antioxidant activity of L. pedunculata subsp. lusitanica EOs was poorer than other Lavandula EOs from Portugal.

show abstract

“…Bibliometric analysis is not a new way of evaluating research output. It has been utilized extensively with different terminologies (Harzing, 2010;Gul et al, 2015). Thus, the bibliometric analysis could provide guidance not only to the novice researcher in the field but also could show a trend of research in the field.…”

Section: Introductionmentioning

confidence: 99%

A Systematic Review on City Liveability Global Research in the Built Environment: Publication and Citation Matrix

Adam

Ghafar

Ahmed

et al. 2017

JDBE

View full text Add to dashboard Cite

This study is an investigation of urban liveability issues in the city development. The study focuses on the appraisal of global research output on urban liveability over the period of 35 years . Bibliometric methods had been carried out to identify and evaluate the productivity of top authors, document types, journals, countries, affiliations, and sources. Data were extracted from scholarly literature published in the leading indexing databases namely -Thomson Reuter's Web of Science and Elsevier's SciVerse Scopus. In this note, a quantitative review of the outstanding global research output in the liveability related field to show a major trend of research and shed light on future direction. Data were analysed, presented and discussed the common characteristics in the top journals, hot, and highly cited articles and the focus areas including common keywords across the studies, researched and under-researched fields. The results revealed, ever since 2005, liveability research output is steadily increasing, with 2015 as the most prolific year. Australia, England, and the USA are the most productive countries. Urban Geography, Urban Design International, and International Development Planning Review are the leading journals in the field. While continuous research interest is prevalent in liveability related field with global collaborative potentials, areas receiving the least research attention such as urban transportation, education, and resiliency could give a directional trend for future urban studies. Liveability Research Matrix established in this research were aimed to guide future research in finding the gap across global context, areas and multi-disciplinary.

show abstract

Research output on Lavender, 2008–2012

Cited by 7 publications

References 40 publications

Integrating Zebrafish Model to Screen Active Ingredients and Network Pharmacology Methods to Explore the Mechanism of Lavandula angustifolia Therapy for Alzheimer's Disease

Integrating Zebrafish Model to Screen Active Ingredients and Network Pharmacology Methods to Explore the Mechanism of Lavandula angustifolia Therapy for Alzheimer's Disease

Essential oils of spontaneous species of the genus Lavandula from Portugal: a brief review

A Systematic Review on City Liveability Global Research in the Built Environment: Publication and Citation Matrix

Contact Info

Product

Resources

About