Research progress of detection technology for illegal addition of prohibited substances in cosmetics

Zhang, Yao; Xie, Sen-Sen; Wu, Yicheng; Liang, Qian-Wen; Xie, Xu-Ting; Luo, Zi-Hang; Liang, Zhan-Hang; Liu, Mingshi

doi:10.1088/1755-1315/559/1/012030

Cited by 4 publications

(4 citation statements)

References 14 publications

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“…They are allowed to be used even if their use must comply with corresponding use conditions (i.e., content limit, use scope). The detection of these compounds is important for the industries that have to check the product quality of cosmetics, ensuring their safety and protecting the consumers' health [34]. Among substances that may harm the consumer, steroids represent prohibited components in cosmetics since they can affect the biological processes in humans even at a very low level.…”

Section: Detection Of Prohibited and Restricted Cosmetic Ingredientsmentioning

confidence: 99%

Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring

et al. 2021

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Cosmetics analysis represents a rapidly expanding field of analytical chemistry as new cosmetic formulations are increasingly in demand on the market and the ingredients required for their production are constantly evolving. Each country applies strict legislation regarding substances in the final product that must be prohibited or regulated. To verify the compliance of cosmetics with current regulations, official analytical methods are available to reveal and quantitatively determine the analytes of interest. However, since ingredients, and the lists of regulated/prohibited substances, rapidly change, dedicated analytical methods must be developed ad hoc to fulfill the new requirements. Research focuses on finding innovative techniques that allow a rapid, inexpensive, and sensitive detection of the target analytes in cosmetics. Among the different methods proposed, immunological techniques are gaining interest, as they make it possible to carry out low-cost analyses on raw materials and finished products in a relatively short time. Indeed, immunoassays are based on the specific and selective antibody/antigen reaction, and they have been extensively applied for clinical diagnostic, alimentary quality control and environmental security purposes, and even for routine analysis. Since the complexity and variability of the matrices, as well as the great variety of compounds present in cosmetics, are analogous with those from food sources, immunological methods could also be applied successfully in this field. Indeed, this would provide a valid approach for the monitoring of industrial production chains even in developing countries, which are currently the greatest producers of cosmetics and the major exporters of raw materials. This review aims to highlight the immunological techniques proposed for cosmetics analysis, focusing on the detection of prohibited/regulated compounds, bacteria and toxins, and allergenic substances, and the identification of counterfeits.

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Section: Detection Of Prohibited and Restricted Cosmetic Ingredientsmentioning

confidence: 99%

Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring

et al. 2021

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“…With the development of the economy and people’s pursuit of beauty, the cosmetics industry has experienced significant growth [ 1 , 2 ]. Despite stringent regulations, such as China’s Cosmetic Safety Technical Specifications and the European Union’s Cosmetic Regulation 1223/2009, which prohibit hazardous ingredients—including lead, mercury, arsenic, antibiotics, hormones, and carcinogens [ 3 , 4 , 5 ]—illicit products continue to infiltrate the market, posing potential dermatological risks and severe health hazards to consumers [ 6 , 7 , 8 , 9 , 10 ]. According to the China National Medical Products Administration, 601 batches of non-compliant cosmetics were detected in 2023, 79 of which contained unauthorized ingredients [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Decoding Cosmetic Complexities: A Comprehensive Guide to Matrix Composition and Pretreatment Technology

Du,

He,

Chen

et al. 2024

Molecules

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Despite advancements in analytical technologies, the complex nature of cosmetic matrices, coupled with the presence of diverse and trace unauthorized additives, hinders the application of these technologies in cosmetics analysis. This not only impedes effective regulation of cosmetics but also leads to the continual infiltration of illegal products into the market, posing serious health risks to consumers. The establishment of cosmetic regulations is often based on extensive scientific experiments, resulting in a certain degree of latency. Therefore, timely advancement in laboratory research is crucial to ensure the timely update and adaptability of regulations. A comprehensive understanding of the composition of cosmetic matrices and their pretreatment technologies is vital for enhancing the efficiency and accuracy of cosmetic detection. Drawing upon the China National Medical Products Administration’s 2021 Cosmetic Classification Rules and Classification Catalogue, we streamline the wide array of cosmetics into four principal categories based on the following compositions: emulsified, liquid, powdered, and wax-based cosmetics. In this review, the characteristics, compositional elements, and physicochemical properties inherent to each category, as well as an extensive overview of the evolution of pretreatment methods for different categories, will be explored. Our objective is to provide a clear and comprehensive guide, equipping researchers with profound insights into the core compositions and pretreatment methods of cosmetics, which will in turn advance cosmetic analysis and improve detection and regulatory approaches in the industry.

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“…Although the cosmetic industry is facing opportunities, cosmetic safety is still facing great challenges. According to “Regulations on the Supervision and Administration of Cosmetics in China” and “Cosmetic regulations of the European Union (regulation 1223/2009)”, some substances, such as lead, mercury, arsenic and their compounds, phthalate plasticizers, antibiotics, hormones, nitrosamines, carcinogenic substances, as well as dioxane are forbidden components in cosmetics [ 1 , 2 , 3 ]. However, there are still many illegal cosmetics containing prohibited substances in recent years.…”

Section: Introductionmentioning

confidence: 99%

“…In addition, there are some comments on the analytical methods for special types of ingredients in cosmetics, such as oils [ 20 ], fragrances [ 21 ], parabens [ 22 ], dyes [ 23 ], and endocrine-disrupting chemicals [ 24 ]. Even though the pretreatment and analytical methods are summarized in detail, the analytical methods are mainly covering traditional confirmation techniques, such as liquid chromatography (LC) methods and LC with mass spectrometry (LC-MS) or tandem mass spectrometry (LC-MS/MS), rare attention is paid on the emerging analytical technologies represented by rapid detection approaches [ 2 , 19 , 25 ].…”

Section: Introductionmentioning

confidence: 99%

Advances on Hormones in Cosmetics: Illegal Addition Status, Sample Preparation, and Detection Technology

Wang

et al. 2023

Molecules

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Owing to the rapid development of the cosmetic industry, cosmetic safety has become the focus of consumers’ attention. However, in order to achieve the desired effects in the short term, the illegal addition of hormones in cosmetics has emerged frequently, which could induce skin problems and even skin cancer after long-term use. Therefore, it is of great significance to master the illegal addition in cosmetics and effectively detect the hormones that may exist in cosmetics. In this review, we analyze the illegally added hormone types, detection values, and cosmetic types, as well as discuss the hormone risks in cosmetics for human beings, according to the data in unqualified cosmetics in China from 2017 to 2022. Results showed that although the frequency of adding hormones in cosmetics has declined, hormones are still the main prohibited substances in illegal cosmetics, especially facial masks. Because of the complex composition and the low concentration of hormones in cosmetics, it is necessary to combine efficient sample preparation technology with instrumental analysis. In order to give the readers a comprehensive overview of hormone analytical technologies in cosmetics, we summarize the advanced sample preparation techniques and commonly used detection techniques of hormones in cosmetics in the last decade (2012–2022). We found that ultrasound-assisted extraction, solid phase extraction, and microextraction coupled with chromatographic analysis are still the most widely used analytical technologies for hormones in cosmetics. Through the investigation of market status, the summary of sample pretreatment and detection technologies, as well as the discussion of their development trends in the future, our purpose is to provide a reference for the supervision of illegal hormone residues in cosmetics.

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Research progress of detection technology for illegal addition of prohibited substances in cosmetics

Cited by 4 publications

References 14 publications

Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring

Immunological Analytical Techniques for Cosmetics Quality Control and Process Monitoring

Decoding Cosmetic Complexities: A Comprehensive Guide to Matrix Composition and Pretreatment Technology

Advances on Hormones in Cosmetics: Illegal Addition Status, Sample Preparation, and Detection Technology

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