Research progress on metabolomics in the quality evaluation and clinical study ofPanax ginseng

Abstract

Panax ginseng, an essential component of traditional medicine and often referred to as the king of herbs, has played a pivotal role in medicine globally for several millennia. Previously, traditional phytochemical methods were mainly used for quality evaluation and pharmacological mechanism studies of ginseng, resulting in the lack of systematicness and innovation and hindering the development and utilization of ginseng resources. Since the beginning of the new century, systems biology technology represented by metabolomics has shown unique advantages in the modernization and internationalization of herbal medicine, establishing a bridge for communication between traditional medicine and modern medicine. P. ginseng, a special herb used in medicine and food, is one of the main research objects for qualitative and quantitative analysis of metabolomics and has gradually become the focus of researchers globally. Here, we conducted a comprehensive summary and analysis of numerous studies published in ginseng metabolomics. This review aims to provide more novel ideas for the quality evaluation, development, and clinical application of ginseng in the future and offer more useful technical references for the modernization and internationalization of herbal medicine based on metabolomics.

Improvement of Panax notoginseng saponin accumulation triggered by methyl jasmonate under arbuscular mycorrhizal fungi

“…F. H. Chen, belonging to the genus Panax , family Araliaceae, is a highly valued perennial medicinal herb plant that is widely distributed in Yunnan Province, China, of which the taproots are the main medicinal parts. Saponins are the main active substances and have remarkable pharmacological value and biological activities in animal experiments or clinical treatment, e.g., cardioprotective effects, protection against cerebrovascular injury, neuroprotective effects, anti-tumor, anti-inflammatory activities, hemostasis and anti-coagulation ( Liu et al., 2020 ; Jiang et al., 2021 ; Cheng et al., 2023 ; Xia Z. et al., 2023 ).…”