Research Progress on Risk Factors and Treatment Strategies for the Coexistence of Osteoporosis in COPD Patients

Abstract

Osteoporosis (OP) is a systemic condition that can be induced by chronic obstructive pulmonary disease (COPD), further exacerbating the condition in COPD patients, impacting prognosis and quality of life, and increasing the risk of potential mortality. Early symptoms of OP are not evident, leading to potential treatment oversight. Early diagnosis of OP in COPD patients holds crucial clinical significance. This article summarizes the risk factors and treatment progress of COPD patients with concomitant OP. The risk factors for COPD patients with concomitant OP mainly include smoking, inflammatory response, age, medication effects, vitamin D deficiency, gender, lack of exercise, hypoxemia, body mass index, hormone levels, oxidative stress, and others. Currently, the basic treatment principle for COPD combined with OP is to manage both conditions simultaneously, integrating OP treatment into the COPD treatment plan. Commonly used anti-OP medications are categorized into those promoting bone formation, mineralization, and inhibiting bone resorption. Traditional Chinese medicine has also shown considerable efficacy in the treatment of COPD combined with OP.