Resection status and margin control in intraoperative frozen sectioning analysis of oral squamous cell carcinoma
Felix Neumann,
Xenia Straub,
Friedrich Mrosk
et al.
Abstract:Purpose
Intraoperative frozen section analysis (IFSA) is a well-established procedure for determining the intraoperative soft tissue resection status in patients with oral squamous cell carcinoma (OSCC). Margin status is a major predictor of the patient´s outcome, histologically free margins of ≥ 5 mm are demanded. This study evaluates the accuracy of IFSA, the impact of margin status and the impact of intraoperative margin revision on disease-free survival (DFS) and overall survival (OS).
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