Residential exposure to traffic noise and risk of incident atrial fibrillation: A cohort study

Monrad, Maria; Sajadieh, Ahmad; Christensen, Johnny; Ketzel, Matthias; Raaschou-Nielsen, Ole; Tjønneland, Anne; Overvad, Kim; Loft, Steffen; Sørensen, Mette

doi:10.1016/j.envint.2016.04.039

Cited by 63 publications

(28 citation statements)

References 44 publications

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“…Heart failure is a condition that represents the end stage of other conditions, such as hypertension, coronary artery diseases, and arrhythmias. We have previously found associations between the two pollutants and myocardial infarction, stroke, and atrial fibrillation in the present cohort, whereas we found no clear relationship with blood pressure ( Monrad et al 2016 ; Roswall et al 2017 ; Sørensen et al 2011 , 2014 ). When investigating whether a known existing cardiovascular condition modified the relationship between the exposures and risk of heart failure, we found that especially people who were hypertensive at baseline were susceptible to the hazardous effects of air pollution and, potentially, also noise, on risk of heart failure.…”

Section: Discussioncontrasting

confidence: 95%

Long-Term Exposure to Road Traffic Noise and Nitrogen Dioxide and Risk of Heart Failure: A Cohort Study

Sørensen

Nielsen

Sajadieh

et al. 2017

Environ Health Perspect

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Background:Although air pollution and road traffic noise have been associated with higher risk of cardiovascular diseases, associations with heart failure have received only little attention.Objectives:We aimed to investigate whether long-term exposure to road traffic noise and nitrogen dioxide (NO2) were associated with incident heart failure.Methods:In a cohort of 57,053 people 50–64 y of age at enrollment in the period 1993–1997, we identified 2,550 cases of first-ever hospital admission for heart failure during a mean follow-up time of 13.4 y. Present and historical residential addresses from 1987 to 2011 were found in national registers, and road traffic noise (normalLden) and NO2 were modeled for all addresses. Analyses were done using Cox proportional hazard model.Results:An interquartile range higher 10-y time-weighted mean exposure for normalLden and NO2 was associated with incidence rate ratios (IRR) for heart failure of 1.14 (1.08–1.21) and 1.11 (1.07–1.16), respectively, in models adjusted for gender, lifestyle, and socioeconomic status. In models with mutual exposure adjustment, IRRs were 1.08 (1.00–1.16) for normalLden and 1.07 (1.01–1.14) for NO2. We found statistically significant modification of the NO2–heart failure association by gender (strongest association among men), baseline hypertension (strongest association among hypertensive), and diabetes (strongest association among diabetics). The same tendencies were seen for noise, but interactions were not statistically significant.Conclusions:Long-term exposure to NO2 and road traffic noise was associated with higher risk of heart failure, mainly among men, in both single- and two-pollutant models. High exposure to both pollutants was associated with highest risk. https://doi.org/10.1289/EHP1272

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Section: Discussioncontrasting

confidence: 95%

Long-Term Exposure to Road Traffic Noise and Nitrogen Dioxide and Risk of Heart Failure: A Cohort Study

Sørensen

Nielsen

Sajadieh

et al. 2017

Environ Health Perspect

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“…The relationship between road traffic noise and incident atrial fibrillation was also evaluated in a Danish prospective study, showing that an increase in noise levels per 10 dB was associated with a 6% (IRR: 1.06, 95% CI: 1.00–1.12) higher risk; however, this relationship was not independent of exposure to air pollution [47]. Since the growing demand for mobility is not only related to noise but also air pollution, it is important to differentiate between these two exposures in terms of evaluating health effects.…”

Section: Epidemiological Evidence For Health Effects Of Noisementioning

confidence: 99%

Environmental Noise-Induced Effects on Stress Hormones, Oxidative Stress, and Vascular Dysfunction: Key Factors in the Relationship between Cerebrocardiovascular and Psychological Disorders

Hahad

Prochaska

Daiber

et al. 2019

Oxidative Medicine and Cellular Longevity

192

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The role of noise as an environmental pollutant and its adverse effects on health are being increasingly recognized. Beyond its direct effects on the auditory system (e.g., hearing loss and tinnitus induced by exposure to high levels of noise), chronic low-level noise exposure causes mental stress associated with known cardiovascular complications. According to recent estimates of the World Health Organization, exposure to traffic noise is responsible for a loss of more than 1.5 million healthy life years per year in Western Europe alone, a major part being related to annoyance, cognitive impairment, and sleep disturbance. Underlying mechanisms of noise-induced mental stress are centered on increased stress hormone levels, blood pressure, and heart rate, which in turn favor the development of cerebrocardiovascular disease such as stroke, arterial hypertension, ischemic heart disease, and myocardial infarction. Furthermore, traffic noise exposure is also associated with mental health symptoms and psychological disorders such as depression and anxiety, which further increase maladaptive coping mechanisms (e.g., alcohol and tobacco use). From a molecular point of view, experimental studies suggest that traffic noise exposure can increase stress hormone levels, thereby triggering inflammatory and oxidative stress pathways by activation of the nicotinamide adenine dinucleotide phosphate oxidase, uncoupling of endothelial/neuronal nitric oxide synthase inducing endothelial and neuronal dysfunction. This review elucidates the mechanisms underlying the relationship between noise exposure and cerebrocardiovascular and psychological disorders, focusing on mental stress signaling pathways including activation of the autonomous nervous system and endocrine signaling and its association with inflammation, oxidative stress, and vascular dysfunction.

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“… 15 Recently, road traffic noise has been found to increase the risk for other major CVD not evaluated by WHO, most importantly heart failure and atrial fibrillation. 14 , 16 Aircraft noise has also been associated with higher CVD incidence and mortality, 14 , 17 but due to a limited number of studies, the evidence is still rated low to moderate. 18 …”

Section: Pathophysiology and Epidemiology Of Noise And Cardiovascularmentioning

confidence: 99%

Reduction of environmental pollutants for prevention of cardiovascular disease: it’s time to act

Münzel

Miller

Sørensen

et al. 2020

European Heart Journal

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Residential exposure to traffic noise and risk of incident atrial fibrillation: A cohort study

Cited by 63 publications

References 44 publications

Long-Term Exposure to Road Traffic Noise and Nitrogen Dioxide and Risk of Heart Failure: A Cohort Study

Long-Term Exposure to Road Traffic Noise and Nitrogen Dioxide and Risk of Heart Failure: A Cohort Study

Environmental Noise-Induced Effects on Stress Hormones, Oxidative Stress, and Vascular Dysfunction: Key Factors in the Relationship between Cerebrocardiovascular and Psychological Disorders

Reduction of environmental pollutants for prevention of cardiovascular disease: it’s time to act

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