DOI: 10.58530/2022/0774
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Resolve fiber crossings using orientation distribution function (ODF) of decomposed sub-voxel paramagnetic and diamagnetic susceptibility

Abstract: DECOMPOSE-QSM was applied on high angular-resolution multi-echo gradient-echo data of a chimpanzee brain to evaluate its ability in resolving orientation mixture of substructure fiber bundles. The orientation distribution function (ODF) of the separated paramagnetic and diamagnetic susceptibility provides smooth transitions of multiple fiber orientations. Additionally, the paramagnetic maps from DECOMPOSE show a potential to resolve fiber crossings in deep gray matter regions.

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