Restless legs syndrome

Ondo, William G.

doi:10.1007/s11910-005-0071-7

Cited by 35 publications

(33 citation statements)

References 98 publications

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“…This result is in agreement with Ondo (2015) who reported that leg cramps symptoms are generally worse in the evening & at night (35) . Moreover, kanaan and Sawaya (2001) stated that leg cramps commonly happen at night where the plantar flexed foot places the calf, ventral foot muscles in the most shortened and (36) .…”

Section: Effect Of Reflexology Foot Massage On Leg Cramps For Patientsupporting

confidence: 92%

Effect of Reflexology Foot Massage on Leg Cramps for Patients on Hemodialysis.

El-Deeb¹,

Donia²,

Zeid³

et al. 2017

IOSR JNHS

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Section: Effect Of Reflexology Foot Massage On Leg Cramps For Patientsupporting

confidence: 92%

Effect of Reflexology Foot Massage on Leg Cramps for Patients on Hemodialysis.

El-Deeb¹,

Donia²,

Zeid³

et al. 2017

IOSR JNHS

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“…In most cases, serum ferritin and iron-binding saturation should be obtained for serum iron deficiency, and electrolytes should be obtained for renal failure 5 . Familial cases of RLS demonstrating autosomal dominant pattern of inheritance are well-know described.…”

mentioning

confidence: 99%

Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations

Guerreiro

Nishikawa

Ferreira

et al. 2010

Arq. Neuro-Psiquiatr.

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Restless legs syndrome (RLS) is a neurological disorder that responds to dopaminergic drugs, indicating a common pathophysiology with Parkinson's disease (PD). The prevalence of RLS was estimated in a group of PD patients and its clinical and biochemical characteristics were analysed. Forty-eight patients with PD were evaluated into two groups, with and without RLS. Clinical characteristics assessed in both groups were age, gender, duration of PD, Hoehn and Yahr, and Schwab and England scales. Laboratory variables such as hemoglobin, s-iron, s-ferritin and creatinine were obtained. The prevalence of RLS was 18.75%. No significant differences regarding clinical variables and biochemical parameters were observed. The high prevalence of RLS found in PD patients suggests the concept of a common etiological link and it seems that secondary causes did not play a central role in the pathophysiology of RLS in this group of parkinsonian patients. Key words: restless legs syndrome, Parkinson's disease, prevalence, ferritin.Síndrome das pernas inquietas na doença de Parkinson: características clínicas e correlações bioquímicas RESUMO A síndrome das pernas inquietas (SPI) é um distúrbio sensitivo-motor que responde aos agentes dopaminérgicos, demonstrando uma possível semelhança fisiopatológica com a doença de Parkinson (DP). Foi avaliada a prevalência da SPI em um grupo de pacientes com DP e suas características clínicas e laboratoriais. Quarenta e oito pacientes diagnosticados com DP foram divididos em dois grupos: com e sem SPI. Características clínicas como idade, sexo, duração da DP, escalas de Hoehn e Yahr, e Schwab e England e achados bioquímicos como hemoglobina, ferro sérico, ferritina sérica e creatinina foram obtidos. A freqüência da SPI foi de 18,75%. Não se observaram diferenças estatisticamente significativas quanto às características clínicas e aos achados bioquímicos. A alta prevalência de SPI encontrada em pacientes com DP sugere associação entre essas duas doenças. É provável que causas secundárias não exerçam papel central na fisiopatologia da SPI nesse grupo de pacientes parkinsonianos. Palavras-chave: síndrome das pernas inquietas, doença de Parkinson, prevalência, ferritina.

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“…Long-term studies of RLS treatment outcomes have focused primarily on effects of medication [32][33][34][35][36][37][38] , but the findings have been inconsistent. Whereas some studies have reported a marked decrease in RLS [37] and outstanding efficacy of RLS-related medication [32] , others have reported an increase in symptoms [35] , or only symptomatic relief rather than any curative effect [32] .…”

Section: Discussionmentioning

confidence: 99%

Unfavorable Polysomnographic Sleep Patterns Predict Poor Sleep and Poor Psychological Functioning 3 Years Later in Patients with Restless Legs Syndrome

Brand

Beck

Hatzinger³

et al. 2010

Neuropsychobiology

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Background: Amongst the variety of disorders affecting sleep, restless legs syndrome (RLS) merits particular attention. Little is known about long-term outcomes for sleep or psychological functioning following a diagnosis of RLS. The aim of the present study was thus to evaluate sleep and psychological functioning at a 3-year follow-up and based on polysomnographic measurements. Method: Thirty-eight patients (18 female and 20 male patients; mean age: 56.06, SD = 12.07) with RLS and sleep electroencephalographic recordings were followed-up 33 months later. Participants completed a series of self-rating questionnaires related to sleep and psychological functioning. Additionally, they completed a sleep log for 7 consecutive days. Results: Age, male gender, increased light sleep (S1, S2) and sleep onset latency, along with low sleep efficiency, predicted psychological functioning and sleep 33 months later. Specifically, sleep fragmentation predicted poor psychological functioning, and both sleep fragmentation and light sleep predicted poor sleep. Conclusions: In patients with RLS, irrespective of medication or duration of treatment, poor objective sleep patterns at diagnosis predicted both poor psychological functioning and poor sleep about 3 years after diagnosis. The pattern of results suggests the need for more thorough medical and psychotherapeutic treatment and monitoring of patients with RLS.

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Restless legs syndrome

Cited by 35 publications

References 98 publications

Effect of Reflexology Foot Massage on Leg Cramps for Patients on Hemodialysis.

Effect of Reflexology Foot Massage on Leg Cramps for Patients on Hemodialysis.

Restless legs syndrome in Parkinson's disease: clinical characteristics and biochemical correlations

Unfavorable Polysomnographic Sleep Patterns Predict Poor Sleep and Poor Psychological Functioning 3 Years Later in Patients with Restless Legs Syndrome

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