Restricted access mesoporous magnetic polypyrrole for extraction of acid, neutral and basic compounds from whey

Restricted access polypyrrole employed in pipette-tip solid-phase extraction for determination of nimodipine and nicardipine in breast milk

“…Besides, HMs showed an absorption band at around 1700 cm −1 referring to the bond CO and CAS showed a band at around 1683 cm −1 due to CN stretching, which confirms the presence of crosslinking between casein and glutaraldehyde and band attributed to the carboxylate group (O–C–O) at 1415 cm −1 . 20–22,27,28…”

“…PPy and PPy–HM showed an apparently similar structure (spongy), which changed considerably after coating with CAS, confirming that a RAM has been successfully obtained. 20–22…”

“…In both studies, recoveries close to 100% and excellent protein exclusion capacities were archived. 20,21…”

“…The surface of PPy has been modied with hydrophilic groups (HMs) or protein layers such as casein (CAS) or bovine serum albumin (BSA). [20][21][22] Our research group introduced new materials based on PPy doubly coated with HMs and CAS/BSA, which were used as adsorbents for the analysis of diclofenac, pronil and febantel in whey/milk samples and for the analysis of progesterone, pyriproxyfen and deltamethrin in chicken eggs. In both studies, recoveries close to 100% and excellent protein exclusion capacities were archived.…”

“…In both studies, recoveries close to 100% and excellent protein exclusion capacities were archived. 20,21 In this perspective, the main objective of this work was to synthesize and characterize a new RAM based on PPy and use it in PT-SPE for simultaneous determination of NIM and NIC in breast milk samples by HPLC-UV. This adsorbent has been characterized by Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), surface analysis, point zero charge (pH PZC ), thermogravimetric analysis (TGA) and wettability.…”