Résultats à deux ans de la trabéculoplastie sélective au laser dans le glaucome à angle ouvert et l’hypertonie oculaire

Zaninetti, Marc; Ravinet, Emilie

doi:10.1016/s0181-5512(08)74744-2

Cited by 9 publications

(2 citation statements)

References 16 publications

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“…These results contrast evidence from a subsequent study, which compared 17 POAG/NTG patients with 11 XFG patients. All subjects were poorly controlled on medical therapy and were followed up for 2 years [ 25 ]. These authors documented that at the end of the follow-up period, XFG patients achieved a significantly greater 28.2% IOP reduction from baseline (from a mean IOP of 18.8 mmHg) with a mean 1.88 topical medications compared with 15.2% reduction from the pre-laser value (17.1 mmHg) with a mean 1.27 topical medications for patients with POAG or NTG.…”

Section: Efficacy Of Slt In Eyes With Xfgmentioning

confidence: 99%

A Review of the Clinical Usefulness of Selective Laser Trabeculoplasty in Exfoliative Glaucoma

et al. 2018

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In the last decade, selective laser trabeculoplasty (SLT) has been commonly used in the management of several different types of glaucoma, as either primary or adjunct therapy. The technique has an excellent safety profile and is at least as effective as argon laser trabeculoplasty. Although the actual mechanism of action of SLT remains unclear, evidence has shown that it does not induce morphologically evident trabecular meshwork alterations. SLT's non-disruptive mode of action offers the advantage of repeatability. Exfoliation glaucoma (XFG) is a secondary open-angle glaucoma with unfavorable intraocular pressure (IOP) characteristics, which typically carries a poorer long-term prognosis than primary open-angle glaucoma. Consequently, patients with XFG often need multiple medications to achieve IOP levels that prevent disease progression. Because complicated pharmacotherapy regimens undermine the long-term tolerability and compliance of patients with XFG, options such as SLT may decrease the burden of multiple therapies and ultimately improve prognosis. In fact, SLT may be a particularly attractive option in XFG because the pigment-laden trabecular tissue of these patients enhances the absorption of laser energy and thus augments the biologic effects induced by this treatment. The current article reviews the postulated mechanisms of action of SLT, discusses practical aspects of SLT therapy, and examines selected peer-reviewed literature pertaining to the clinical usefulness of this modality in XFG patients.

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Section: Efficacy Of Slt In Eyes With Xfgmentioning

confidence: 99%

A Review of the Clinical Usefulness of Selective Laser Trabeculoplasty in Exfoliative Glaucoma

et al. 2018

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“…This was unexpected since patients with PEXG often have highly pigmented trabecular meshwork. There are studies suggesting a greater effect of SLT in eyes with a higher degree of angle pigmentation as this results in greater absorption of laser energy (Kara et al, 2013; Wasyluk et al, 2014; Zaninetti & Ravinet, 2008). However, several studies show similar treatment response in eyes with POAG and PEXG (Ayala & Chen, 2011; Koucheki & Hashemi, 2012; Shazly et al, 2010).…”

Section: Discussionmentioning

confidence: 99%

Long‐term follow‐up of laser trabeculoplasty in multi‐treated glaucoma patients

Rasmuson

Bengtsson

Lindén

et al. 2023

Acta Ophthalmologica

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PurposeTo evaluate the long‐term effect of laser trabeculoplasty (LTP) in patients randomized to multi‐treatment in the Glaucoma Intensive Treatment Study (GITS).MethodsPatients with untreated newly diagnosed open‐angle glaucoma were treated with three intraocular pressure (IOP)‐lowering substances for 1 week and then 360° argon or selective LTP was performed. IOP was measured just before LTP and repeatedly during the 60‐month study period. Our previous report on 12 months follow‐up data revealed no effect of LTP in eyes having an IOP <15 mmHg before the laser treatment.ResultsBefore LTP, the mean IOP ± standard deviation in all 152 study‐eyes of 122 multi‐treated patients was 14.0 ± 3.5 mmHg. Three eyes of three deceased patients were lost to follow‐up during the 60 months. After exclusion of eyes that received increased therapy during follow‐up, the IOP was significantly reduced at all visits up to 48 months in eyes with pre‐LTP IOP ≥15 mmHg; 2.6 ± 3.1 mmHg at 1 month and 1.7 ± 2.8 mmHg at 48 months, n = 56 and 48, respectively. No significant IOP reduction was seen in eyes with pre‐LTP IOP <15 mmHg. Seven eyes, i.e., <13%, with pre‐LTP IOP ≥15 mmHg at baseline had required increased IOP‐lowering therapy at 48 months.ConclusionLTP performed in multi‐treated patients may provide a useful IOP reduction that is maintained over several years. This was true on a group level when the initial IOP was ≥15 mmHg, but if the pre‐laser IOP was lower than that, chances of LTP success were small.

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La trabéculoplastie au laser sélectif (TLS) : notre expérience chez le noir africain

Seck

Agboton

Dieng

et al. 2015

Journal Français d'Ophtalmologie

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Résultats à deux ans de la trabéculoplastie sélective au laser dans le glaucome à angle ouvert et l’hypertonie oculaire

Cited by 9 publications

References 16 publications

A Review of the Clinical Usefulness of Selective Laser Trabeculoplasty in Exfoliative Glaucoma

A Review of the Clinical Usefulness of Selective Laser Trabeculoplasty in Exfoliative Glaucoma

Long‐term follow‐up of laser trabeculoplasty in multi‐treated glaucoma patients

La trabéculoplastie au laser sélectif (TLS) : notre expérience chez le noir africain

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