Résultats à long terme de la résection des polypes endométriaux chez 367 patientes. Place de l'endométrectomie associée

Polena, Viola; Mergui, J.-L.; Zerat, Laurent; Daraı̈, Émile; Barranger, Emmanuel; Uzan, Serge

doi:10.1016/j.gyobfe.2005.04.021

Cited by 15 publications

(2 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previously published studies of polypectomy for treating abnormal uterine bleeding have reported success rates of 60-100%,12 21 22 23 24 25 26 27 28 which are similar to the 73% and 80% reported in this study. However, these were mainly small, cohort studies of patients undergoing inpatient polypectomy with general anaesthesia.…”

Section: Discussionsupporting

confidence: 88%

Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study

Cooper

Clark

Middleton

et al. 2015

BMJ

View full text Add to dashboard Cite

ObjeCtive To compare the effectiveness and acceptability of outpatient polypectomy with inpatient polypectomy. DesignPragmatic multicentre randomised controlled noninferiority study.setting Outpatient hysteroscopy clinics in 31 UK National Health Service hospitals.PartiCiPants 507 women who attended as outpatients for diagnostic hysteroscopy because of abnormal uterine bleeding and were found to have uterine polyps.interventiOns Participants were randomly assigned to either outpatient uterine polypectomy under local anaesthetic or inpatient uterine polypectomy under general anaesthesia. Data were collected on women's self reported bleeding symptoms at baseline and at 6, 12, and 24 months. Data were also collected on pain and acceptability of the procedure at the time of polypectomy. Main OutCOMe MeasuresThe primary outcome was successful treatment, determined by the women's assessment of bleeding at six months, with a prespecified non-inferiority margin of 25%. Secondary outcomes included generic (EQ-5D) and disease specific (menorrhagia multi-attribute scale) quality of life, and feasibility and acceptability of the procedure. results 73% (166/228) of women in the outpatient group and 80% (168/211) in the inpatient group reported successful treatment at six months (intention to treat relative risk 0.91, 95% confidence interval 0.82 to 1.02; per protocol relative risk 0.92, 0.82 to 1.02). Failure to remove polyps was higher (19% v 7%; relative risk 2.5, 1.5 to 4.1) and acceptability of the procedure was lower (83% v 92%; 0.90, 0.84 to 0.97) in the outpatient group Quality of life did not differ significantly between the groups. Four uterine perforations, one of which necessitated bowel resection, all occurred in the inpatient group. COnClusiOnsOutpatient polypectomy was non-inferior to inpatient polypectomy. Failure to remove a uterine polyp was, however, more likely with outpatient polypectomy and acceptability of the procedure was slightly lower. trial registratiOnInternational Clinical Trials Registry 65868569.

show abstract

Section: Discussionsupporting

confidence: 88%

Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study

Cooper

Clark

Middleton

et al. 2015

BMJ

View full text Add to dashboard Cite

show abstract

“…TCRP 4 has little damages to endometrium and can effectively relieve menstrual disorder. 5 But TCRP alone cannot thoroughly resect endometrial polyp and is unable to effectively inhibit the supply of blood to endometrial polyp, leading to higher recurrence rate. 6 Previous studies have suggested that short-acting or slowly released progesterone hormone in combination with hysteroscopic resection was significantly effective in preventing postoperative recurrence of endometrial polyp.…”

Section: Introductionmentioning

confidence: 99%

Post hysteroscopic progesterone hormone therapy in the treatment of endometrial polyps

Wei

Yang

et al. 2018

Pak J Med Sci

View full text Add to dashboard Cite

Objective:To find out the clinical effects of post hysteroscopic progesterone hormone therapy in the treatment of endometrial polyps in terms of clinical outcome and the expression of endometrial Vascular Endothelial Growth Factor (VEGF).Methods:Ninety-eight patients who were confirmed as endometrial polyp in the hospital from April 2014 and December 2016 were selected and divided into treatment group and a control group using random number table, 49 in each group. Patients in both groups were given hysteroscopic operation. Patients in the treatment group were treated by progesterone hormone drugs after hysteroscopic operation, while patients in the control group were not given progesterone hormone. The changes of menstrual blood volume, menstrual cycle and expression of VEGF were compared between the two groups after treatment, and the recurrence condition, thickness of endometrium and hemoglobin were followed up one year after treatment.Results:The pictorial blood loss assessment chart (PBAC) scores of patients in the two groups had no significant difference before treatment (P>0.05); but the score of the treatment group was much lower than that of the control group. The improvement rate of menstrual cycle of the treatment group was much higher than that of the control group, and the difference had statistical significance (P<0.05). Compared to before treatment, the serum VEGF level of the patients in both groups had a remarkable decline in the 1st, 3rd and 6th month after treatment, and the difference had statistical significance (P<0.05). The difference of the serum VEGF level between the two groups in the 1st and 3rd month after treatment had no statistical significance (P>0.05). The serum VEGF level of the treatment group was notably lower than that of the control group six months after treatment, and the difference had statistical significance (P<0.05). The follow-up results demonstrated that the treatment group had smaller thickness of endometrium and higher level of hemoglobin compared to the control group, and the recurrence rate of the treatment group was lower than that of the control group (P<0.05).Conclusion:Post hysteroscopic progesterone hormone therapy has favorable clinical effect in treating endometrial polyps as it can effectively prevent the recurrence of endometrial polyps, relieve the level of hemoglobin and reduce endometrial thickness.

show abstract

Hysteroscopic Instrumentation

Istre¹,

Thurkow²

2014

Minimally Invasive Gynecological Surgery

View full text Add to dashboard Cite

Résultats à long terme de la résection des polypes endométriaux chez 367 patientes. Place de l'endométrectomie associée

Cited by 15 publications

References 26 publications

Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study

Outpatient versus inpatient uterine polyp treatment for abnormal uterine bleeding: randomised controlled non-inferiority study

Post hysteroscopic progesterone hormone therapy in the treatment of endometrial polyps

Hysteroscopic Instrumentation

Contact Info

Product

Resources

About