Results from the Survey of Antibiotic Resistance (SOAR) 2011–13 in Ukraine

Feshchenko, Y. I.; Dzyublik, A.; Pertseva, Tetyana; Bratus, E; Dzyublik, Y.; Gladka, G.; Morrissey, Ian; Torumkuney, D

doi:10.1093/jac/dkw068

Cited by 13 publications

(9 citation statements)

References 15 publications

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“…Published studies in the field originate from large tertiary care centers [153][154][155][156][157][158][159][160]. The Surveys of Antibiotic Resistance (SOAR) (2016-2017) conducted to determine the antibiotic susceptibility of S. pneumonia, and H. influenzae isolates from communityacquired respiratory tract infections showed high susceptibility to tested antibiotics and an increase in antibiotic resistance to trimethoprim/sulfamethoxazole and macrolides among S. pneumoniae [161][162][163][164]. The survey data considered the EUCAST/CLSI and pharmacokinetics and pharmacodynamics breakpoints165.…”

Section: A Snapshot Of Amr Surveillance Programs and The Epidemiologymentioning

confidence: 99%

Surveillance of antimicrobial resistance in low- and middle-income countries: a scattered picture

Iskandar

Molinier

Hallit

et al. 2021

Antimicrob Resist Infect Control

235

144

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Data on comprehensive population-based surveillance of antimicrobial resistance is lacking. In low- and middle-income countries, the challenges are high due to weak laboratory capacity, poor health systems governance, lack of health information systems, and limited resources. Developing countries struggle with political and social dilemma, and bear a high health and economic burden of communicable diseases. Available data are fragmented and lack representativeness which limits their use to advice health policy makers and orientate the efficient allocation of funding and financial resources on programs to mitigate resistance. Low-quality data means soaring rates of antimicrobial resistance and the inability to track and map the spread of resistance, detect early outbreaks, and set national health policy to tackle resistance. Here, we review the barriers and limitations of conducting effective antimicrobial resistance surveillance, and we highlight multiple incremental approaches that may offer opportunities to strengthen population-based surveillance if tailored to the context of each country.

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Section: A Snapshot Of Amr Surveillance Programs and The Epidemiologymentioning

confidence: 99%

Surveillance of antimicrobial resistance in low- and middle-income countries: a scattered picture

Iskandar

Molinier

Hallit

et al. 2021

Antimicrob Resist Infect Control

235

144

View full text Add to dashboard Cite

show abstract

“…The Survey of Antibiotic Resistance has provided findings about AMR in various countries and reported the distribution among MICs including MIC50 and MIC90 [ 3 , 15 , 18 – 25 ]. According to these previous studies, S .…”

Section: Introductionmentioning

confidence: 99%

Improved penicillin susceptibility of Streptococcus pneumoniae and increased penicillin consumption in Japan, 2013–18

et al. 2020

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Objectives To examine the association between penicillin susceptibility of Streptococcus pneumoniae and penicillin consumption in Japan. Methods We used Japan Nosocomial Infection Surveillance data on the susceptibility of S . pneumoniae and sales data obtained from IQVIA Services Japan K.K. for penicillin consumption. We analysed both sets of data by decomposing them into seasonality and chronological trend components. The cross-correlation function was checked using Spearman’s rank correlation coefficient to examine the correlation between susceptibility and consumption. Results After adjusting for seasonality, the susceptibility of S . pneumoniae to penicillins gradually improved (55.7% in 2013 and 60.6% in 2018, respectively) and penicillin consumption increased during the same period (0.76 defined daily doses per 1,000 inhabitants per day [DID] in 2013, and 0.89 DID in 2018). The results showed positive cross-correlation (coefficient 0.801, p -value < 0.001). In contrast, cephalosporin consumption decreased (3.91 DID in 2013 and 3.19 DID in 2018) and showed negative cross-correlation with susceptibility of S . pneumoniae to penicillins (coefficient −0.981, p -value < 0.001). Conclusions The rates of penicillin-susceptible S . pneumoniae isolates did not negatively correlate with penicillin consumption at the population level. Increased penicillin consumption might not impair the penicillin susceptibility of S . pneumoniae .

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“…However, due to the high risk of injuries from these methods, conservative therapy (with antibiotics and glucocorticosteroids) is now used (Bulfamante et al 2019). Treatment of CPR should begin with the eradication of the pathogen, considering the resistance of the micro-organism and the pharmacological effect of antibiotics (Feshchenko et al 2016;Grayson et al 2019;Iqbal et al 2020). Currently (according to the Eurasian Clinical Recommendations 2016, which are still currently), antibiotics used for the treatment of infectious diseases of the upper respiratory tract are usually divided into 3 lines of therapy (Song et al 2019):…”

Section: Treatmentmentioning

confidence: 99%

Modern approaches to the treatment of chronic polypous rhinosinusitis

Bairashevskaia¹,

Kytko²,

Vasil’ev³

et al. 2020

RRP

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Introduction: Today, chronic polypous rhinosinusitis (CPR) occupies a special place among otolaryngological diseases, the incidence rate of which increases every year. To date, the main causes of chronic polypous rhinosinusitis are Staphylococcus aureus and anatomical abnormalities. Diagnostics: Knowledge of a universal algorithm for the diagnosis of this disease, consisting of the collection of anamnesis, endoscopic examination of the nasal cavity, computed tomography of the paranasal sinuses, anterior active rhinomanometry and bacteriological determination of the microbial spectrum, allows diagnosing chronic polyposis rhinosinusitis in time, and, as a consequence, to prescribe a treatment. Treatment: This review describes conservative therapies, including antibiotics and glucocorticosteroids. Today, the main task of doctors is to find the most effective method of administration of glucocorticosteroids to achieve the maximum effect. One of these methods is the introduction of the drug with the help of nebulizer, as in this case, the drug will remain in the perirhinal cavity for a long time and have the maximum effect due to the directed action only in the area of the pathological process. Features of chronic polypous rhinosinusitis in childhood: It should be noted that children under 12 years of age due to the formation of the paranasal sinuses at different stages of ontogenesis will be characterized by different forms of chronic polyposis rhinosinusitis. That is why they should be known and taken into account when making a diagnosis and prescribing a treatment. Conclusion: Today, the frequency of chronic rhinosinusitis increases exponentially, which makes the question of the modern approach to its treatment the most relevant. It is possible that additional research in this area will solve the issue of searching for both the optimal path of therapy and treatment of CPR in children.

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Results from the Survey of Antibiotic Resistance (SOAR) 2011–13 in Ukraine

Cited by 13 publications

References 15 publications

Surveillance of antimicrobial resistance in low- and middle-income countries: a scattered picture

Surveillance of antimicrobial resistance in low- and middle-income countries: a scattered picture

Improved penicillin susceptibility of Streptococcus pneumoniae and increased penicillin consumption in Japan, 2013–18

Modern approaches to the treatment of chronic polypous rhinosinusitis

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