Resveratrol: Enough to Explain the French Paradox?

Horseradish peroxidase (HRP) as a tool in green chemistry

“…In the mid-1990s, trans-resveratrol (45) was iden-tied as one of the possible factors responsible for the French Paradox concept. 93 Naturally its biotransformation using HRP and hydrogen peroxide was studied and trans-d-viniferin (46), a resveratrol-trans-dehydrodimer was obtained as the major product (Scheme 14). 94 Other studies can be found where this important polyphenolic compound was used as HRP substrate and, for instance, its dimeric structure (+)-3-viniferin was also tested.…”