2013
DOI: 10.1097/iae.0b013e31827d2509
|View full text |Cite
|
Sign up to set email alerts
|

Retinal Architecture Recovery After Grid Photocoagulation in Diabetic Macular Edema Observed in Vivo by Spectral Domain Optical Coherence Tomography

Abstract: In vivo imaging of morphologic lesion repair in human eyes after PASCAL grid laser of diabetic macular edema demonstrates progressive restoration of the external limiting membrane and inner segment/outer segment integrity as previously described in animal models.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

1
8
0

Year Published

2014
2014
2021
2021

Publication Types

Select...
6

Relationship

1
5

Authors

Journals

citations
Cited by 10 publications
(9 citation statements)
references
References 42 publications
1
8
0
Order By: Relevance
“…In the past, researchers monitoring the in vivo healing process of outer retinal layers following grid photocoagulation using OCT have found that the ELM and IS/OS progressively recovered to an intact continuous state and also observed the proliferation and migration of RPE cells to the center of the lesions over time [5,6]. e results of our study are consistent with these findings.…”
Section: Discussionsupporting
confidence: 91%
See 1 more Smart Citation
“…In the past, researchers monitoring the in vivo healing process of outer retinal layers following grid photocoagulation using OCT have found that the ELM and IS/OS progressively recovered to an intact continuous state and also observed the proliferation and migration of RPE cells to the center of the lesions over time [5,6]. e results of our study are consistent with these findings.…”
Section: Discussionsupporting
confidence: 91%
“…During the initial phase of laser photocoagulation, the laser-induced thermal damage is confined to the outer retina, including the photoreceptor and retinal pigment epithelium (RPE) [4]. However, previous studies conducted in both rabbits and humans have revealed that retinal morphology can be gradually repaired following laser photocoagulation [4][5][6][7][8].…”
Section: Introductionmentioning
confidence: 99%
“…6 ). This disruption is repaired in about 50% of the cases within 3 months after photocoagulation therapy, but clearly highlights the destructive nature of photocoagulation [46] .…”
Section: Evidencementioning
confidence: 99%
“…11 A different study of the same group revealed that 3 months following treatment, the laser-induced changes were confined to the lower PR level. 12 Cyst formation and diffuse swelling in the inner and outer nuclear layers were still detectable to some extent. Approximately 2 months following treatment, the IS/OS and external limiting membrane became continuous again.…”
Section: Discussionmentioning
confidence: 97%