Retinal Complications Associated With Pars Plana Vitrectomy for Macular Holes or Epiretinal Membranes in Eyes With Previous Retinal Detachment Repair

Singh, Ravi Shankar; Covert, Douglas J.; Henry, Christopher R.; Bhatia, S. K.; Croskrey, Jason A.; Sanchez, C. R.

doi:10.1001/jamaophthalmol.2013.5698

Cited by 2 publications

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The duration of diabetes directly correlates with the increased risk of the developing this complication, with patients of type 1 diabetes being more susceptible than type 2 diabetic patients . The present clinical treatments of diabetic retinopathy are limited to laser photocoagulation and vitrectomy . Although in the last two decades, researchers have targeted a number of preventive agents such as anti‐vascular endothelial growth factor (VEGF) agents, anti‐TNF‐alpha agents, peroxisome proliferator‐activated receptor (PPAR)‐gamma receptor agonists, all these agents are still on preclinical or clinical testing stages.…”

Section: Introductionmentioning

confidence: 99%

“…[1] The present clinical treatments of diabetic retinopathy are limited to laser photocoagulation and vitrectomy. [2,3] Although in the last two decades, researchers have targeted a number of preventive agents such as anti-vascular endothelial growth factor (VEGF) agents, anti-TNF-alpha agents, peroxisome proliferator-activated receptor (PPAR)-gamma receptor agonists, all these agents are still on preclinical or clinical testing stages. One of the successful agents clinically established now are the anti-VEGF agents which primarily act by restricting/inhibiting angiogenesis.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Chinese herbal drugs for the treatment of diabetic retinopathy

Behl

Kotwani

2017

Journal of Pharmacy and Pharmacology

View full text Add to dashboard Cite

Objectives To explore the various pharmacological actions and the molecular mechanisms behind them by which Chinese herbs tend to lower the risk of developing microvascular diabetic complications in retina and prevent its further progression. Key findings Several Chinese herbs, indeed, elicit potent anti-inflammatory, antioxidant, anti-angiogenic, anti-apoptotic, peroxisome proliferator-activated receptor-gamma receptor agonistic, platelet-activating factor antagonistic, aldose reductase inhibitory and various other beneficial pharmacological activities, required to counteract the pathological conditions prevalent in retina during diabetes. Summary Chinese herbs can potentially be used for the treatment/prevention of diabetic retinopathy owing to the virtue of numerous properties by which they alleviate several hyperglycaemia-induced pathological occurrences in retina. This would provide a natural and safe therapy for diabetic retinopathy, which currently is clinically limited to destructive techniques like laser photocoagulation and vitrectomy.

show abstract

Section: Introductionmentioning

confidence: 99%