Retinal Endovascular Surgery for Central Retinal Vein Occlusion

Bynoe, Leon A.; Hutchins, Robert K.; Lazarus, Howard S.; Friedberg, Mark A.

doi:10.1097/00006982-200507000-00014

Cited by 70 publications

(37 citation statements)

References 12 publications

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“…This technique works by several different mechanisms: firstly, pars plana vitrectomy with removal of posterior hyaloid provides high oxygen levels to retina, relieves macular traction and contributes to resolution of macular edema ; secondly, direct injection of t-PA causes lyses of trombus by providing high local concentration and thirdly, bolus of t-PA may flush out the trombus with its high flow velocity [21] . Similarly, Bynoe et al [22] revealed favorable results with retinal endovascular surgery.…”

Section: Introductionmentioning

confidence: 83%

Fibrinolytic and Surgical Treatment Approaches for Retinal Vein Occlusion

Tekin¹,

Teke²,

İnanç³

2016

International Journal of Ophthalmic Research

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Retinal vein occlusion (RVO) is the second most common vascular disease after diabetic retinopathy. Although its high frequency, mechanisms underlying RVO and optimal treatment strategies are still controversial. There are various treatment modalities for retinal vein occlusion including observation, systemic treatments, intravitreal agents, laser photocoagulation, fibrinolytic treatment and surgical approaches. Despite most of the treatment strategies are directed at secondary complications of RVO that affect vision including macular edema and retinal neovascularization, some treatment options also have the ability to create a bypass around the obstructed retinal vein and to decrease the raised venous hydrostatic pressure. The aim of this review is to describe the outcomes of fibrinolytic and surgical treatment modalities for RVO.

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Section: Introductionmentioning

confidence: 83%

Fibrinolytic and Surgical Treatment Approaches for Retinal Vein Occlusion

Tekin¹,

Teke²,

İnanç³

2016

International Journal of Ophthalmic Research

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“…Among a variety of surgical tools in ophthalmic operations, the beveled needle is a widely used surgical instrument for delivering the drug into micro-structural anatomies of the eye such as retinal blood vessels and sub-retinal areas. Many studies have been carried out with significant progress in the needle segmentation through microscopic images [5][6][7][8]. These works achieved satisfactory results using either color-based or geometry-based features.…”

Section: Introductionmentioning

confidence: 99%

Needle Segmentation in Volumetric Optical Coherence Tomography Images for Ophthalmic Microsurgery

et al. 2017

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Needle segmentation is a fundamental step for needle reconstruction and image-guided surgery. Although there has been success stories in needle segmentation for non-microsurgeries, the methods cannot be directly extended to ophthalmic surgery due to the challenges bounded to required spatial resolution. As the ophthalmic surgery is performed by finer and smaller surgical instruments in micro-structural anatomies, specifically in retinal domains, difficulties are raised for delicate operation and sensitive perception. To address these challenges, in this paper we investigate needle segmentation in ophthalmic operation on 60 Optical Coherence Tomography (OCT) cubes captured during needle injection surgeries on ex-vivo pig eyes. Furthermore, we developed two different approaches, a conventional method based on morphological features (MF) and a specifically designed full convolution neural networks (FCN) method, moreover, we evaluate them on the benchmark for needle segmentation in the volumetric OCT images. The experimental results show that FCN method has a better segmentation performance based on four evaluation metrics while MF method has a short inference time, which provides valuable reference for future works.

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“…These vessels have a cross section diameter of 80µm. A promising treatment is the injection of clot-dissolving drugs such as, tissue Plasminogen Activator (tPA) directly into the affected vessel [2]. Wei et al suggested a method using stenting as a surgical solution for Central Retinal Vein Occlusion (CRVO) [3].…”

Section: Introductionmentioning

confidence: 99%

The introduction of a new robot for assistance in ophthalmic surgery

Nasseri

Eder

Nair

et al. 2013

2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)

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Abstract-This paper introduces the design and development of a new robotic system to assist surgeons performing ophthalmic surgeries. The robot itself is very compact and similar to an average human hand in size. Its primary application is intraocular micromanipulation in order to overcome the existing challenges in treatment of diseases like Retinal Vein Occlusion (RVO). The novel hybrid mechanism designed for this robot allows microscale motions and is stable in the presence of vibrations common in operation room (OR). The robotic system can be easily integrated into standard operation rooms and does not require modification of conventional surgical tools. This compact microsurgical system is suitable for mounting on the patient's head and thereby, solves the problem of patient motion. The compatibility of the robotic system with a real world surgical setup was evaluated and confirmed in this work.

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Retinal Endovascular Surgery for Central Retinal Vein Occlusion

Cited by 70 publications

References 12 publications

Fibrinolytic and Surgical Treatment Approaches for Retinal Vein Occlusion

Fibrinolytic and Surgical Treatment Approaches for Retinal Vein Occlusion

Needle Segmentation in Volumetric Optical Coherence Tomography Images for Ophthalmic Microsurgery

The introduction of a new robot for assistance in ophthalmic surgery

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