Retinal Nerve Fiber Layer Thickness in a Subset of Karachi (Pakistan) Population

Mukhtar, Sahrish; Hassan, Nuzhat; Dawood, Zafar; Zehra, Nosheen

doi:10.9734/bjmmr/2015/20525

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Reported mean RNFL thickness of normal Pakistani population in various local studies was 94.46 µm, 99.02 µm and 102.38 µm using Topcon 3D Mark II-1000, Spectralis Heidelberg and Stratus OCT respectively 7,10,17. RNFL thickness values in our study were found to be lower than these values both in control and PXF group.…”

Section: Discussioncontrasting

confidence: 42%

Comparison of retinal nerve fiber layer thickness in patients having pseudo exfoliation syndrome with healthy adults

Yasmeen

Fatima

Islam³

2016

Pak J Med Sci

View full text Add to dashboard Cite

Objective:To compare mean retinal nerve fiber layer (RNFL) thickness in patients having pseudo exfoliation (PXF) with normal age matched controls using spectral domain optical coherence tomography (SD-OCT).Methods:This was a case control study conducted at Armed Forces Institute of Ophthalmology (AFIO) Rawalpindi from 12 June 2013 to 12 January 2014. Seventy eyes (Group A - 35 patients with PXF and Group B - 35 healthy age matched subjects) of more than 40 years of age were included in the study. Intraocular pressure (IOP) was measured with Goldmann applanation tonometer (GAT) and peripapillary RNFL thickness was measured in four quadrants with SD-OCT (Topcon 3D OCT-1000 Mark II) in all subjects. Data was analyzed using the SPSS version 14.Results:Mean age of group A (PXF patients) was 65.63 ± 8.47 years and of group B (Healthy subjects) was 64.31 ± 6.51 years (p = 0.470). Both groups were gender matched with male preponderance (p = 0.673). Mean IOP in each group was 13.80 ± 2.59 mm Hg, and 13.49 ± 2.07 mm Hg respectively (p= 0.578). Mean average peripapillary RNFL thickness was 77.46 ± 12.17 µm in group A and 83.96 ± 10.58 µm in group B. Statistically significant differences were detected between two groups for mean average RNFL thickness (p= 0.020) and mean RNFL thickness in inferior quadrant (p=0.014).Conclusion:PXF patients with normal IOP and visual fields have thin RNFL as compared to healthy age matched controls. Therefore routine assessment and follow up of PXF patients with OCT may help in early diagnosis of PXF glaucoma.

show abstract

Section: Discussioncontrasting

confidence: 42%