Retinal Nerve Fibre Layer and Macular Thicknesses in Adults with Hyperopic Anisometropic Amblyopia

Yakar, Konuralp; Kan, Emrah; Alan, Aydın; Hanifi, Mehmet; Ceylan, Tolga

doi:10.1155/2015/946467

Cited by 17 publications

(10 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study, there was no significant difference noted in TMT between amblyopic and control eyes. Similar findings were reported in some studies [4,9,10], whereas Yi et al [3] reported that the fovea of amblyopic eye tend to be thicker than that of the normal fellow eye, while the inner and outer macula tend to be thinner. The difference in the results of these studies may be due to the experimental design, ethnicity, or refractive error.…”

Section: Discussionsupporting

confidence: 89%

Thicknesses of macular inner retinal layers in children with anisometropic amblyopia

Xia

Chen

Zheng³

2019

Preprint

View full text Add to dashboard Cite

Background To investigate the thicknesses of macular inner retinal layers in children with anisometropic amblyopia through spectral-domain optical coherence tomography (SD-OCT). Methods Thirty-seven children with anisometropic amblyopia and fifty-seven children with normal vision participated in the study. Both eyes of children with amblyopia and the right eyes of children with normal vision underwent scanning with the Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany). The segmentation of retinal layers was performed automatically to measure individual inner retinal layers in the five sectors of the macula. An independent-sample t-test was used to compare measurements of anisometropic eyes and fellow eyes with control eyes. Results There was no significant difference in the total macular thickness in the five sectors between amblyopic and control eyes. However, in the peripheral macular area, three of the four quadrants of both the ganglion cell layer (GCL) and the inner plexiform layer (IPL) thickness were significantly reduced in amblyopic eyes than in control eyes. Moreover, two of the four quadrants of the GCL thickness and three of the four quadrants of the IPL thickness in the peripheral macular area were significantly reduced in fellow eyes than in control eyes. Conclusions The SD-OCT data revealed differences in the thicknesses of some macular inner retinal layers in both eyes of children with anisometropic amblyopia compared with those with emmetropia, indicating that structural changes might exist in the retina of children with amblyopia.

show abstract

Section: Discussionsupporting

confidence: 89%

Thicknesses of macular inner retinal layers in children with anisometropic amblyopia

Xia

Chen

Zheng³

2019

Preprint

View full text Add to dashboard Cite

show abstract

“… 14 , 40 , 41 In contrast to these results, other studies reported that the difference in the macular thickness between the hypermetropic amblyopic and the normal eyes was negligible. 13 , 32 , 42 , 43 The same higher values regarding RNFLT were found in hypermetropic amblyopic eyes with a significant difference from the normal eyes. These results are parallel to some studies 8 , 37 , 44 and contrast to the other ones.…”

Section: Discussionsupporting

confidence: 61%

“…Numerous previous studies have dealt with the changes in anisometropic amblyopia with different results. 40 – 43 In the present study, the hypermetropic amblyopic eyes exhibited a thicker CMT, thicker average macular thickness, and higher macular volume than the normal eyes. These findings are in agreement with the previous results of different studies, which formerly demonstrated a greater macular thickness in hypermetropic-affected eyes.…”

Section: Discussionsupporting

confidence: 48%

See 1 more Smart Citation

Changes in macular parameters in different types of amblyopia: optical coherence tomography study

Kasem¹,

Badawi²

2017

OPTH

View full text Add to dashboard Cite

PurposeThe purposes of this study were to investigate the changes in macular parameters (thickness, volume) and peripapillary retinal nerve fiber layer (RNFL) thickness (RNFLT) in different cases of amblyopia versus the normal fellow eyes using optical coherence tomography (OCT) and to estimate the relationship of OCT changes with various defined patients’ parameters.DesignThis is a prospective, observational, cross-sectional case series.MethodsThe method involved measuring the peripapillary RNFLT, macular thickness, and macular volume via spectral domain (OCT) in different types of amblyopia and comparing with the other fellow eyes. This study was conducted at the Mansoura Ophthalmic Center.ResultsA total of 64 patients with different types of amblyopia were included. The mean central macular thickness (CMT) was 196.2±50.03 µm in the amblyopic eyes versus 167±12.76 µm in the fellow eyes (P=0.000), the mean average macular thickness was 265.80±12.77 µm in the amblyopic eyes versus 259.10±3.09 µm in the fellow eyes (P=0.000), the mean macular volume was 7.59±0.32 mm3 in the amblyopic eyes versus 7.34±0.071 mm3 in the fellow eyes (P=0.002), and the mean global RNFLT was 97.00±11.60 µm in the amblyopic eyes versus 78.50±13.05 µm in the fellow eyes (P=0.029). There was a discrepancy between the different amblyopic types. Age and the axial length were the only independent variables that statistically significantly correlated with the CMT.ConclusionThe unilateral amblyopic eyes were prone to have a higher CMT and thicker global RNFL compared to those of the sound fellow eyes. Retinal variations between different types of the amblyopia differ from one type to another. The age could be considered as a predictor of the disease worsening and treatment prognosis. Further studies are required to emphasize these results.

show abstract

“…Also, there are scientists like Kee (2006) Repka (2009), Firat (2013) and Yakar (2015) who claim the inexistence of differences between amblyopic patients and the control group in their studies regarding macula morphology [ 15 - 18 ].…”

Section: Resultsmentioning

confidence: 99%

CAN Optical Coherence Tomography redefine amblyopia?

Avram¹

2017

rjo

View full text Add to dashboard Cite

REVIEW 95Results: 19 research studies focused on macular and nerve optic changes, 7 on choroidal changes and 6 on retinal changes after occlusion. The results were discussed according to the type of amblyopia, alteration of macular thickness, optic nerve changes, ganglion cell layer changes, and alteration of choroidal thickness. Conclusions:The results are of great variability, and it seems that macula and choroid involvement is more frequently suggested compared with optic nerve involvement.

show abstract

Retinal Nerve Fibre Layer and Macular Thicknesses in Adults with Hyperopic Anisometropic Amblyopia

Cited by 17 publications

References 31 publications

Thicknesses of macular inner retinal layers in children with anisometropic amblyopia

Thicknesses of macular inner retinal layers in children with anisometropic amblyopia

Changes in macular parameters in different types of amblyopia: optical coherence tomography study

CAN Optical Coherence Tomography redefine amblyopia?

Contact Info

Product

Resources

About