Retinal Vasculitis and Posterior Pole Preretinal Exudates in Exogenous Bacterial Endophthalmitis: Management and Visual Outcomes

Chen, Kuan‐Jen; Chen, Yen‐Po; Wang, Nan-Kai; Sun, Ming‐Hui; Sun, Chi-Chin; Wu, Wei‐Chi; Lai, Chi-Chun

doi:10.1080/09273948.2020.1814343

Cited by 5 publications

(7 citation statements)

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“…One patient (patient 3) had condensed posterior pole preretinal exudates and retinal detachment, and became phthisic in last visit. We previously reported that acute endophthalmitis with severe vitritis are typically associated with condensed posterior pole preretinal exudates, which might be associated with poor visual outcomes [ 17 ].…”

Section: Discussionmentioning

confidence: 99%

Staphylococcus lugdunensis Endophthalmitis: Case Series and Literature Review

et al. 2022

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Staphylococcus lugdunensis endophthalmitis is an uncommon intraocular infection with potentially visually devastating consequences. S. lugdunensis endophthalmitis have been reported following cataract surgery, trauma, intravitreal injections of anti-vascular endothelial growth factor agents and dexamethasone implant. We report four cases of postoperative S. lugdunensis endophthalmitis after cataract extraction (three patients) and combined pars plana vitrectomy and cataract extraction (one patient). The onset of presentation of endophthalmitis was acute (within 2 weeks) in two patients, subacute (2 to 6 weeks) in one patient, and chronic (more than 6 weeks) in one patient. All patients had presenting visual acuity (VA) of hand motions or worse and were treated with pars plana vitrectomy with intravitreal antibiotics. The final VA was 20/50 in two patients, 4/200 in one patient with pre-existing myopic maculopathy, and no light perception in one patient with retinal detachment. In antibiotic susceptibility testing, S. lugdunensis isolates were resistant to penicillin (3/4, 75%), but all were susceptible to vancomycin, oxacillin, teicoplanin, tigecycline, and sulfamethoxazole-trimethoprim. S. lugdunensis may be associated with acute or chronic endophthalmitis. Favorable visual outcomes can be achieved with prompt diagnosis and management.

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Section: Discussionmentioning

confidence: 99%

Staphylococcus lugdunensis Endophthalmitis: Case Series and Literature Review

et al. 2022

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“…Bu nedenle postoperatif dönemde detaylı muayene ve düzenli takip edilmeyen olgular gözden kaçabilmekte, tedaviye rağmen geri dönüşümsüz ciddi görme kayıpları gelişebilmektedir. 4,5 Parsplana vitrektomilerden (PPV) sonra gelişen endoftalmilerin insidansı cerrahi tekniklere, preoperatif ve postoperatif uygulanan profilaktik yöntemlere, mikroorganizmanın patojenitesine, endoftalmi tanısının konulma zamanına, yöntemlerine ve hastaların immün yapısı gibi değişen faktörlere göre değişiklik göstermektedir. 3,5 CURRENT RETINA -GÜNCEL RETINA…”

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“…4,5 Parsplana vitrektomilerden (PPV) sonra gelişen endoftalmilerin insidansı cerrahi tekniklere, preoperatif ve postoperatif uygulanan profilaktik yöntemlere, mikroorganizmanın patojenitesine, endoftalmi tanısının konulma zamanına, yöntemlerine ve hastaların immün yapısı gibi değişen faktörlere göre değişiklik göstermektedir. 3,5 CURRENT RETINA -GÜNCEL RETINA…”

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Endophthalmitis After Vitreoretinal Surgery

KOÇAK ALTINTAŞ

2023

CRJ

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Endophthalmitis after vitreoretinal surgery is uncommon but one of the most serious complications associated with severe visual loss despite appropriate treatment. It can be diagnosed based on symptoms such as ocular pain, conjunctival hyperemia, corneal congestion, corneal edema, anterior chamber inflammation, hypopyon, and vitreous haziness. The most common agents responsible for postoperative endophthalmitis are bacteria from patients' own ocular surface flora. Several factors such as preoperative sterilization, surgical nature of the procedure, intraocular tamponade, and postoperative treatment methods are responsible for the development of endophthalmitis after pars plana vitrectomy. The prognosis of endophthalmitis depends on the virulence of the microorganism, the patients’ immune nature, the time of diagnosis, and the initiation of treatment.

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“…Isolated reports of retinal vascular occlusion following inadvertent injection of mitomycin C during anterior segment surgery, [29][30][31] a direct toxic effect, and after intentional IVT injection of cefuroxime 32 and rituximab 33 have also been described. In this issue of Ocular Immunology & Inflammation (OII), an original article describes a favorable outcome in a patient with HORV following intraocular delivery of vancomycin, 34 while one case report 35 and two letters to the editor 36,37 discuss the appearance of occlusive retinal vasculitis in the setting of bacterial endophthalmitis, thus highlighting the importance of considering infections in patients who develop such findings in similar settings.…”

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confidence: 99%

“…40,41 A similar presentation has been described in cases of bacterial endophthalmitis following IVT injection. 27,42,43 Chen et al 34 retrospectively studied 40 eyes of 40 patients who developed exogenous bacterial endophthalmitis with retinal vasculitis and posterior pole pre-retinal exudates seen over a 10-year period at a tertiary referral center in Taiwan. Preceding events included cataract surgery (n = 30; 75.0%), trauma (n = 5; 12.5%), trabeculectomy (n = 2; 5.0%), and one each (2.5%) for penetrating keratoplasty, pars plana vitrectomy (PPV) and iridoplasty.…”

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confidence: 99%