2022
DOI: 10.1186/s40360-021-00546-2
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RETRACTED ARTICLE: The teratogenic effect of pregabalin on heart, liver and kidney in rats: a light microscopic, electron microscopic and immunohistochemical study

Abstract: Background Pregabalin (PGB) was approved as new anti-epileptic drugs with little information about its teratogenic effect. Aim of the work to evaluate the developmental toxicity of PGB. Materials and methods 60 pregnant albino rats were divided into three groups. PGB (500 mg/kg body weight/day) was given to group II, PGB (1250 mg/kg body weight/day) was given to Group III and no medications were given … Show more

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Cited by 3 publications
(1 citation statement)
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“…In recent years, there have been advancements in the field of seizure prediction, and that has allowed intervention during seizures, such as medications or invasive electrodes [3][4][5]. The drawbacks of such methods include the harmful effects of epileptic drugs on the liver and kidneys [6]; as well as adverse effects on female reproductive organs [7], also using invasive electrodes causes irreversible damage to brain tissues.…”
Section: Introductionmentioning
confidence: 99%
“…In recent years, there have been advancements in the field of seizure prediction, and that has allowed intervention during seizures, such as medications or invasive electrodes [3][4][5]. The drawbacks of such methods include the harmful effects of epileptic drugs on the liver and kidneys [6]; as well as adverse effects on female reproductive organs [7], also using invasive electrodes causes irreversible damage to brain tissues.…”
Section: Introductionmentioning
confidence: 99%