Artificial intelligence is a branch of computer science, which includes natural language, intelligent processing, and professional methods. Since the birth of artificial intelligence, the technology and application fields have continued to grow, and the application fields have also continued to expand. This article aims to study the application of artificial intelligence technology in the management information system of container multimodal transportation and to provide convenient and efficient operation methods for container multimodal transportation. This paper proposes the C-means clustering method. Through the research and development of the terminal management system, it has achieved great success in automation, intelligent planning, and integrated management. At the same time, the EDI system is adopted, which mainly uses the combination of GPS and GIS information platform Internet network technology. Therefore, when evaluating the operation of the multimodal transport virtual container under the control of coproduction, the DEA method is used to operate the multimodal virtual container. The situation is analyzed and evaluated, and the multimodal transport virtual container is determined through investment. The experimental results of this article show that the artificial intelligence system achieves the most efficient multimodal transport management with the most efficient system model, combined with the leading container multimodal transport virtual enterprise, to provide the best way of the management process for the development of the multimodal transport management information system. The intact rate of container cargo during transportation is as high as 99.7%.