RETRACTED: Preoperative microbiologic screening and antibiotic prophylaxis in pulmonary resection operations

Boldt, Joachim; Piper, Swen N.; Uphus, D.; Füssle, Roswitha; Hempelmann, G.

doi:10.1016/s0003-4975(99)00400-2

Cited by 43 publications

(31 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…These results are in contrast to other studies that found antibiotic resistance in 32-50% [18,19] of the patients. This difference could be explained by the fact that most of the patients in the present study had wellpreserved lung function while patients in other studies had a significant degree of airway obstruction, associated with severe exacerbation and frequent antibiotic treatment which may have led to antibiotic resistance [20].…”

Section: Discussioncontrasting

confidence: 99%

Bronchial bacterial colonization in patients with resectable lung carcinoma

Ioanăş¹,

Angrill²,

Baldó³

et al. 2002

Eur Respir J

View full text Add to dashboard Cite

The pattern and clinical implications of bronchial bacterial colonization have been widely investigated in patients with chronic lung disease, particularly chronic obstructive pulmonary disease. The main aim of this study was to determine the frequency and risk factors for bronchial colonization in lung cancer patients who have undergone surgical resection.Forty-one patients with resectable lung cancer (22 (54%) active smokers, 52¡23 pack-yrs) with a mean forced expiratory volume in one second of 80 ¡ 16% predicted, were studied with bilateral protected specimen brush and lung tissue biopsy during the surgical procedure. Quantitative bacterial culture, susceptibility tests and histological examination of samples were performed.Bronchial colonization with o1 potential pathogenic micro-organism was found in 17 of 41 (41%) patients. The most frequent strains isolated were: Haemophilus influenzae (35%), Streptococcus pneumoniae (13%) and Pseudomonas spp. (9%). The risk factors for bronchial colonization were central location of the tumour (odds ratio (OR)=9.2, confidence interval (CI) 95%=2.1-39.6, p=0.003) and increased body mass index (OR=1.6, CI 95%=1.2-2.2, p=0.005). The frequency of postoperative infectious pulmonary complications was low (five cases (12%)) and no relationship was observed with bronchial colonization.Patients with resectable lung carcinoma had a high rate of bronchial colonization (41%), mainly with potential pathogenic microorganisms. The independent risk factors for colonization in these patients were central location of the tumour and a high body mass index.

show abstract

Section: Discussioncontrasting

confidence: 99%

Bronchial bacterial colonization in patients with resectable lung carcinoma

Ioanăş¹,

Angrill²,

Baldó³

et al. 2002

Eur Respir J

View full text Add to dashboard Cite

show abstract

“…According to the patients' general status and suspected underlying disease, prophylactic antibiotic may be given with appropriate dosages [18,21] . Antibiotics should be considered on basis of the suspected pathologies and applied after culture and antibiotic susceptibility results [15,18,21,29,30] .…”

Section: Discussionmentioning

confidence: 99%

“…Antibiotics should be considered on basis of the suspected pathologies and applied after culture and antibiotic susceptibility results [15,18,21,29,30] . In presented study, because pulmonary infection risk was evaluated, the antibiotic was not applied to dogs due to study plan at 0, 24 and 48 th h. However, considering to antibiotic susceptibility results of a previous study [21] , a selective antibiotic (ampicillin sulbactam) was applied to all dogs both prophylactically and as treatment protocol.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Pulmoner Kontüzyonlu Köpeklerde Pulmoner Enfeksiyon Riskinin Değerlendirilmesi

Salcı¹,

Demirbilek²,

Cetin³

et al. 2017

Kafkas Univ Vet Fak Derg

View full text Add to dashboard Cite

There is a dilemma about usage and selection of the antibiotics following pulmonary contusion. Thus, this study aimed to evaluate pulmonary infection risk in dogs with pulmonary contusion. In total, eleven dogs with pulmonary contusion included in the study. Diagnosis of the pulmonary contusion and its degrees were determined based on the clinical and radiological findings. Under general anesthesia, bronchoscopy and bronchoalveolar lavage (BAL) was applied on 0, 24 and 48 th h and BAL samples were collected. Cytological examination, culture and antibiotic susceptibility analysis of the BAL samples were performed. Clinically, mild, moderate and severe degree pulmonary contusions were diagnosed, but radiological results pointed out severe degree of pulmonary contusion in all dogs. Bronchoscopy showed the hemoptysis in all dogs except one. Cytologically, all preparations had the inflammatory results at 0 th hour and these were increased at 24 and 48 th hours. Additionally, evidence of infection was determined in the cytological preparations of four dogs (case 1, 2, 5 and 8) taken at 0, 24 and 48 th hours. These cytological results were compatible with microbiological results of case 1, 2, 5 and 8. Pasteurella multocida in case 1 and 2, and Escherichia coli in case 5 and 8 was cultured microorganism from the BAL samples, separately. While P. multocida was resistant to gentamicin, erythromycin and oxytetracycline; E. coli was resistant only sulfamethoxazole/trimethoprim. In conclusion, it may be stated that pulmonary contusion triggers inflammation process, and if there is a pathogenic opportunistic flora in the lower respiratory tracts, the pulmonary infections might accompany with inflammation process. Thus, if it is able, antibiotic usage must be planned considering to the results of BAL culture and antibiogram tests.

show abstract

“…Boldt and colleagues, in 1999, suggested that the best schedule for antibiotic prophylaxis will depend, among other factors, on the bacteria that are present at the time when these patients undergo surgery [32]. They carried out a randomized prospective study in which they compared ampicillin sulbactam (group 1) and cephazoline (group 2).…”

Section: Antibiotic Prophylaxis In Lung-resection Surgerymentioning

confidence: 99%

Respiratory infections after lung cancer resection

Torres¹

2006

Expert Review of Anti-infective Therapy

View full text Add to dashboard Cite

RETRACTED: Preoperative microbiologic screening and antibiotic prophylaxis in pulmonary resection operations

Cited by 43 publications

References 9 publications

Bronchial bacterial colonization in patients with resectable lung carcinoma

Bronchial bacterial colonization in patients with resectable lung carcinoma

Pulmoner Kontüzyonlu Köpeklerde Pulmoner Enfeksiyon Riskinin Değerlendirilmesi

Respiratory infections after lung cancer resection

Contact Info

Product

Resources

About